GlyCosmos Portal

Submissions

phospholipase A2 group IVF

Summary

Gene Symbol

PLA2G4F

Aliases

PLA2G4F/Z

Organism

Homo sapiens (human)

External Links

NCBI Gene

255189

HGNC

27396

KEGG Gene ID

hsa:255189

PubChem

255189

Alliance of Genome Resources

HGNC:27396

JoGo

PLA2G4F

TogoVar

PLA2G4F

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Cytoplasm
Direct protein sequencing
Hydrolase
Lipid degradation
Membrane
Metal-binding
Mitochondrion
Phospholipid degradation
Proteomics identification
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q68DD2	Phospholipase A2 group IVF
A5PKZ7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
prostaglandin biosynthetic process
glycerophospholipid metabolic process	IEA
phospholipid catabolic process	IEA
phosphatidylglycerol acyl-chain remodeling	TAS
glycerophospholipid catabolic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

glycerophospholipid catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

glycerophospholipid catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

catabolic process [inference]

lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

glycerophospholipid catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to antibiotic

response to stimulus [inference]

response to chemical [inference]

response to antibiotic [inference]

cellular response to antibiotic

cellular response to chemical stimulus [inference]

cellular response to antibiotic

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to antibiotic

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

secretion [inference]

icosanoid secretion [inference]

arachidonic acid secretion

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
cytoplasm	IEA
mitochondrion	EXP
mitochondrion	IEA
cytosol	TAS
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

leading edge membrane [inference]

ruffle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
glycerophospholipase activity	IEA
phosphatidylcholine lysophospholipase A1 activity	IEA
A2-type glycerophospholipase activity	IBA
A2-type glycerophospholipase activity	IEA
calcium ion binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

glycerophospholipase activity

A2-type glycerophospholipase activity

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

carboxylic ester hydrolase activity [inference]

A2-type glycerophospholipase activity

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

calcium-dependent phospholipid binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytosolic phospholipase a2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
calcium ion binding
calcium-dependent phospholipase A2 activity
calcium-dependent phospholipid binding
glycerophospholipid catabolic process
hydrolase activity
lipid metabolic process
metal ion binding
phospholipase activity
phospholipid catabolic process

Displaying **all 6** entries
InterPro
Acyl transferase/acyl hydrolase/lysophospholipase
C2 domain superfamily
C2 domain
Cytosolic phospholipase A2, C2 domain
Cytosolic phospholipases A2, C2-domain
Lysophospholipase, catalytic domain

KEGG BRITE Database

Orthology

K16342

Name

cytosolic phospholipase A2 [EC:3.1.1.4]

References

Rhea

RHEA:36231

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

9442064

RHEA:15801

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP004303
Gene Name: phospholipase A2, group IVF

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Saccharomyces cerevisiae S288C	855018	SGD:S000004608
Saccharomyces cerevisiae S288C	855720	SGD:S000004957
Saccharomyces cerevisiae S288C	854151	SGD:S000005371
Saccharomyces cerevisiae S288C	855020	SGD:S000004610