GlyCosmos Portal

solute carrier family 2 member 3

Summary

Gene Symbol

Slc2a3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25551

KEGG Gene ID

PubChem

25551

Alliance of Genome Resources

RGD:3706

Annotation

Keyword

Cell membrane
Cell projection
Glycoprotein
Phosphoprotein
Reference proteome
Sugar transport
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q07647	Glucose transporter type 3, brain
A0A0G2JT05	Glucose transporter type 3
A6ILF8	Glucose transporter type 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
response to glucose	IEP
monosaccharide transmembrane transport	IDA
fructose transmembrane transport	ISS
fructose transmembrane transport	ISO
galactose transmembrane transport	ISS

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

developmental process [inference]

anatomical structure development [inference]

cerebral cortex development

response to stimulus [inference]

response to chemical [inference]

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to Thyroglobulin triiodothyronine

localization [inference]

establishment of localization [inference]

transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

vascular transport [inference]

transport across blood-brain barrier

organic anion transport [inference]

dehydroascorbic acid transport

vitamin transport [inference]

dehydroascorbic acid transport

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
acrosomal membrane	ISO
cytoplasm	ISO
cytoplasm	IDA
plasma membrane	ISS
plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

acrosomal membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

synaptic membrane

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

cell junction [inference]

synapse [inference]

glutamatergic synapse

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
fructose transmembrane transporter activity	ISS
fructose transmembrane transporter activity	ISO
galactose transmembrane transporter activity	ISS
galactose transmembrane transporter activity	ISO
protein binding	IPI

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

carbohydrate transmembrane transporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity

hexose transmembrane transporter activity [inference]

vitamin transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

carbohydrate binding [inference]

monosaccharide binding [inference]

small molecule binding [inference]

monosaccharide binding [inference]

carbohydrate derivative binding [inference]

galactoside binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

solute carrier family 2 (facilitated glucose

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
hexose transmembrane transporter activity

Displaying **all 6** entries
InterPro
Glucose transporter GLUT
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator, sugar transporter-like
Sugar transporter, conserved site
Sugar/inositol transporter

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
synaptic vesicle membrane	PMID:10318820
caveola	PMID:16419038

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	20527	MGI:95757
Drosophila melanogaster	38109	FB:FBgn0264574
Homo sapiens	6515	HGNC:11007
Homo sapiens	144195	HGNC:18301
Saccharomyces cerevisiae S288C	852543	SGD:S000000445

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements