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leptin
Summary
- Gene Symbol
-
- Lep
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| negative regulation of transcription by RNA polymerase II |
|
|
| angiogenesis |
|
|
| angiogenesis |
|
|
| ovulation from ovarian follicle |
|
GO Hierarchy
- regulation of cell cycle
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| obsolete extracellular space |
|
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding |
|
|
| DNA binding |
|
|
| signaling receptor binding |
|
|
| cytokine activity |
|
|
| hormone activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- leptin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Leptin |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2018 | hyperinsulinism | |
| DOID:10605 | short bowel syndrome | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:10603 | glucose intolerance | |
| DOID:14018 | alcoholic liver cirrhosis | |
| DOID:10763 | hypertension | |
| DOID:11476 | osteoporosis | |
| DOID:9970 | obesity | |
| DOID:0050741 | alcohol dependence |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 16846 | MGI:104663 | |
| 3952 | HGNC:6553 |
