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Guidelines

MIRAGE

protein tyrosine phosphatase, receptor type Z1

Summary

Gene Symbol

Ptprz1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25613

KEGG Gene ID

PubChem

25613

Alliance of Genome Resources

RGD:3455

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Phosphoprotein
Protein phosphatase
Proteoglycan
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F1LMY3
Q62656	3F8 chondroitin sulfate proteoglycan 3H1 keratan sulfate proteoglycan Phosphacan

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
hematopoietic progenitor cell differentiation	ISO
protein dephosphorylation	IDA
signal transduction	IBA
axonogenesis	ISO
axonal fasciculation	IDA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell recognition [inference]

neuron recognition [inference]

axonal fasciculation

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

peptidyl-tyrosine dephosphorylation

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

glial cell differentiation [inference]

oligodendrocyte differentiation

cell development [inference]

neuron development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development

neuron projection fasciculation [inference]

axonal fasciculation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

learning [inference]

associative learning [inference]

visual learning

behavior [inference]

learning or memory

learning [inference]

associative learning [inference]

visual learning

visual behavior [inference]

visual learning

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

anatomical structure development [inference]

hippocampus development

cell development [inference]

neuron development

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

glial cell differentiation [inference]

oligodendrocyte differentiation

cell development [inference]

neuron development

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

regulation of glial cell migration [inference]

regulation of Schwann cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

regulation of neuron migration [inference]

positive regulation of neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendrite development

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of dendrite development

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of dendrite development

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendrite morphogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of dendrite development [inference]

negative regulation of developmental process [inference]

negative regulation of dendrite development

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of dendrite development

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cellular process [inference]

signal transduction

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

regulation of cell-substrate adhesion [inference]

negative regulation of cell-substrate adhesion

regulation of myelination

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

negative regulation of cell population proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of neural precursor cell proliferation [inference]

regulation of oligodendrocyte progenitor proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of oligodendrocyte differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendrite development

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

negative regulation of cell population proliferation

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

positive regulation of dendrite development

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of dendrite development [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendrite development

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

regulation of glial cell migration [inference]

regulation of Schwann cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

regulation of neuron migration [inference]

positive regulation of neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of glial cell migration [inference]

positive regulation of Schwann cell migration

positive regulation of neuron migration

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of oligodendrocyte differentiation

Displaying entries **6 - 10** of 22 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
lamellipodium	IDA
filopodium	IDA
axon	IDA
dendrite	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

glutamatergic synapse

external encapsulating structure [inference]

extracellular matrix

specialized extracellular matrix [inference]

synapse-associated extracellular matrix [inference]

perisynaptic extracellular matrix [inference]

perineuronal net

site of polarized growth [inference]

growth cone

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection [inference]

neuron spine [inference]

dendritic spine

actin-based cell projection [inference]

filopodium

cell body [inference]

neuronal cell body

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	ISS
protein tyrosine phosphatase activity	ISO
protein tyrosine phosphatase activity	IDA
protein tyrosine phosphatase activity	IBA
protein tyrosine phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

growth factor binding [inference]

fibroblast growth factor binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying entries **1 - 10** of 11 in total

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Location	References
filopodium	PMID:9660874
neuronal cell body	PMID:8702927
dendritic spine	PMID:15982644
lamellipodium	PMID:9660874
growth cone	PMID:8702927
postsynaptic membrane	PMID:15982644
ruffle membrane	PMID:11381105
axon	PMID:15708477
extracellular space	PMID:15708477
perineuronal net	PMID:16644727

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	19283	MGI:97816
Drosophila melanogaster	43469	FB:FBgn0004369
Homo sapiens	5803	HGNC:9685

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Last updated: April 6, 2026