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ketohexokinase

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25659

KEGG Gene ID

PubChem

25659

Alliance of Genome Resources

RGD:2966

Annotation

Keyword

ATP-binding
Alternative splicing
Carbohydrate metabolism
Direct protein sequencing
Kinase
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A6HAA9
A6HAB0	Hepatic fructokinase
Q02974	Hepatic fructokinase
A0A8I6G7X9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
regulation of glycogen biosynthetic process	ISO
fructose metabolic process	ISO
fructose metabolic process	IDA
fructose metabolic process	IBA
fructose metabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

catabolic process [inference]

carbohydrate catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

carbohydrate catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fructose catabolic process

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to metal ion [inference]

response to zinc ion

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to disaccharide [inference]

response to sucrose

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process

regulation of glycogen biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process

regulation of glycogen biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process

regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	ISO
cytoplasm	ISO
cytoplasm	IBA
cytoplasm	IEA
cytosol	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
ketohexokinase activity	ISO
ketohexokinase activity	TAS
ketohexokinase activity	IDA
ketohexokinase activity	IBA
ketohexokinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

ketohexokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

ketohexokinase activity

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

carbohydrate binding [inference]

monosaccharide binding [inference]

fructose binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

monosaccharide binding [inference]

fructose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:18145

β-D-fructose + ATP

β-D-fructose 1-phosphate + H⁺ + ADP

Enzyme

2.7.1.3

PMID

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	16548	MGI:1096353
Homo sapiens	3795	HGNC:6315

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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