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MIRAGE

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

Summary

Gene Symbol

Plod2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

26432

KEGG Gene ID

PubChem

26432

Alliance of Genome Resources

MGI:1347007

Annotation

Keyword

Cytoplasm
Dioxygenase
Endoplasmic reticulum
Glycoprotein
Iron
Membrane
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Vitamin C

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9R0B9	Lysyl hydroxylase 2
E9Q718

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
response to hypoxia	IEA
collagen fibril organization	IBA
collagen biosynthetic process	ISO
obsolete hydroxylysine biosynthetic process

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

collagen biosynthetic process

collagen metabolic process [inference]

collagen biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

Displaying entries **1 - 5** of 13 in total

1

2

3

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GO Term	Evidence Code	PMID
extracellular region	IBA
obsolete extracellular space
cytoplasm	ISS
cytoplasm	ISO
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

rough endoplasmic reticulum membrane

bounding membrane of organelle [inference]

rough endoplasmic reticulum membrane

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

rough endoplasmic reticulum

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

rough endoplasmic reticulum

Golgi apparatus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
iron ion binding	IEA
procollagen-lysine 5-dioxygenase activity	ISO
procollagen-lysine 5-dioxygenase activity	IBA
procollagen-lysine 5-dioxygenase activity	IEA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

2-oxoglutarate-dependent dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

catalytic activity, acting on a protein [inference]

procollagen-lysine 5-dioxygenase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

procollagen-lysine 2-oxoglutarate 5-dioxygenase 2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 7** entries
Gene Ontology
L-ascorbic acid binding
dioxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
procollagen-lysine 5-dioxygenase activity

Displaying **all 5** entries
InterPro
Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain
Nucleotide-diphospho-sugar transferases
Oxoglutarate/iron-dependent dioxygenase
Procollagen-lysine 5-dioxygenase, conserved site
Prolyl 4-hydroxylase, alpha subunit

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	39265	FB:FBgn0036147
Homo sapiens	5352	HGNC:9082

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026