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growth hormone receptor

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

2690

KEGG Gene ID

PubChem

2690

Alliance of Genome Resources

HGNC:4263

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Dwarfism
Endocytosis
Glycoprotein
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P10912	Somatotropin receptor
A0A087X0H5	Somatotropin receptor
A0A087X162	Somatotropin receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
endocytosis
cell surface receptor signaling pathway via JAK-STAT	ISS
cell surface receptor signaling pathway via JAK-STAT	IEA
positive regulation of cell population proliferation	IBA
response to gravity	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

cytokine-mediated signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

hormone-mediated signaling pathway

metabolic process [inference]

sulfur compound metabolic process [inference]

alkanesulfonate metabolic process [inference]

taurine metabolic process

hormone metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

alkanesulfonate metabolic process [inference]

taurine metabolic process

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis [inference]

receptor internalization

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

cartilage development [inference]

cartilage development involved in endochondral bone morphogenesis

response to stimulus [inference]

response to abiotic stimulus [inference]

response to gravity

response to endogenous stimulus [inference]

response to hormone

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to hormone

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to food

response to lipid [inference]

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to cytokine

response to interleukin-1

response to nitrogen compound [inference]

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to cycloheximide

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to estradiol

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

response to growth hormone

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to alcohol [inference]

response to cycloheximide

response to ketone [inference]

response to cycloheximide

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis

receptor-mediated endocytosis [inference]

receptor internalization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of developmental growth [inference]

regulation of multicellular organism growth

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell differentiation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of developmental process [inference]

positive regulation of cell differentiation

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of response to nutrient levels

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation

regulation of developmental growth [inference]

regulation of multicellular organism growth

positive regulation of multicellular organism growth

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

positive regulation of developmental process [inference]

positive regulation of cell differentiation

positive regulation of developmental growth [inference]

positive regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

cytokine-mediated signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

hormone-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell differentiation

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth

positive regulation of multicellular organism growth

positive regulation of multicellular organismal process [inference]

positive regulation of multicellular organism growth

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process

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GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular region	IDA
extracellular region	IMP
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

growth hormone receptor complex

cellular anatomical structure [inference]

membrane

plasma membrane

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intracellular organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
cytokine receptor activity	IEA
growth hormone receptor activity	ISS
growth hormone receptor activity	IDA
growth hormone receptor activity	IBA
growth hormone receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

growth factor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein tyrosine kinase binding

phosphatase binding [inference]

protein phosphatase binding

protein domain specific binding [inference]

SH2 domain binding

cytokine binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

proline-rich region binding

lipid binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

immune receptor activity [inference]

cytokine receptor activity

growth hormone receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:5353	colonic disease	Alliance of Genome Resources
DOID:0060870	isolated growth hormone deficiency	Alliance of Genome Resources
DOID:13810	familial hypercholesterolemia	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9521	Laron syndrome	Alliance of Genome Resources
DOID:8398	osteoarthritis	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14600	MGI:95708
Rattus norvegicus	25235	RGD:2687

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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