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MIRAGE

myosin IXa

Summary

Gene Symbol

Myo9a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

270163

PubChem

270163

Alliance of Genome Resources

MGI:107735

Annotation

Keyword

ATP-binding
Actin-binding
Alternative splicing
Cell projection
Coiled coil
Cytoplasm
GTPase activation
Myosin
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse
Transmembrane helix
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
D3Z3A8	Unconventional myosin-9a
Q8C170	Unconventional myosin-9a

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
signal transduction	IEA
cell junction assembly	ISS
cell junction assembly	ISO
cell junction assembly	IEA
cell junction organization	IEA

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of monopolar cell polarity [inference]

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment of epithelial cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity [inference]

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of epithelial cell apical/basal polarity [inference]

establishment of epithelial cell apical/basal polarity

establishment or maintenance of monopolar cell polarity [inference]

establishment of monopolar cell polarity [inference]

establishment of apical/basal cell polarity [inference]

establishment of epithelial cell apical/basal polarity

signal transduction

intracellular signal transduction

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation [inference]

establishment of epithelial cell apical/basal polarity

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

postsynaptic specialization organization

cellular component assembly [inference]

cell junction assembly

cell junction organization

cell junction assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation [inference]

establishment of epithelial cell apical/basal polarity

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of neuron projection arborization

regulation of cellular process [inference]

signal transduction

intracellular signal transduction

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of neuron projection arborization

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
cytoplasm	ISO
cytoplasm	IEA
actin filament	IBA
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

cellular anatomical structure [inference]

cell junction [inference]

site of polarized growth [inference]

axonal growth cone

postsynapse

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
microfilament motor activity	IBA
microfilament motor activity	IEA
cytoskeletal motor activity	IEA
actin binding
GTPase activator activity	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity

microfilament motor activity

catalytic activity [inference]

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

polypeptide conformation or assembly isomerase activity [inference]

microfilament motor activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

actin filament binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

actin filament binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin IXB

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
actin filament-based movement
cytoskeletal motor activity
lamellipodium morphogenesis
metal ion binding
nucleotide binding

Displaying entries **1 - 10** of 12 in total

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InterPro
C1-like domain superfamily
Class IX myosin, motor domain
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
Myosin head, motor domain
P-loop containing nucleoside triphosphate hydrolase
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Ras-associating domain
Rho GTPase activation protein
Rho GTPase-activating protein domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1312	focal segmental glomerulosclerosis	Alliance of Genome Resources
DOID:14159	obstructive hydrocephalus	Alliance of Genome Resources

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026