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C-C motif chemokine ligand 7

Summary

Gene Symbol

Ccl7

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

287561

KEGG Gene ID

PubChem

287561

Alliance of Genome Resources

RGD:1359152

Annotation

Keyword

Chemotaxis
Cytokine
Disulfide bond
Glycoprotein
Heparin-binding
Inflammatory response
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9QXY8	Monocyte chemoattractant protein 3 Monocyte chemotactic protein 3 Small-inducible cytokine A7
A6HHD3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
inflammatory response	IBA
immune response	IEA
cytoskeleton organization	ISO
cytoskeleton organization	IEA
canonical NF-kappaB signal transduction

GO Hierarchy

biological process

immune system process [inference]

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

eosinophil migration [inference]

eosinophil chemotaxis

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

G protein-coupled receptor signaling pathway [inference]

chemokine-mediated signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

eosinophil migration [inference]

eosinophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to ethanol

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

response to gamma radiation

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to ethanol

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol [inference]

cellular response to ethanol

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to ethanol

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

chemokine-mediated signaling pathway

G protein-coupled receptor signaling pathway [inference]

chemokine-mediated signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of mononuclear cell migration [inference]

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of natural killer cell chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

positive regulation of mononuclear cell migration [inference]

positive regulation of lymphocyte migration [inference]

positive regulation of lymphocyte chemotaxis [inference]

positive regulation of natural killer cell chemotaxis

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of biological quality [inference]

regulation of cell shape

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
chemokine activity	ISO
chemokine activity	IBA
chemokine activity	IEA
heparin binding
CCR1 chemokine receptor binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

CCR chemokine receptor binding

cytokine receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

CCR chemokine receptor binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2921	glomerulonephritis	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	20306	MGI:99512
Homo sapiens	6354	HGNC:10634

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements