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Guidelines

MIRAGE

ankyrin 3

Summary

Gene Symbol

ANK3

Organism

Homo sapiens (human)

External Links

NCBI Gene

288

PubChem

288

Alliance of Genome Resources

HGNC:494

JoGo

ANK3

TogoVar

ANK3

Annotation

Keyword

3D-structure
ANK repeat
Alternative splicing
Autism spectrum disorder
Cell membrane
Cell projection
Cytoplasm
Cytoskeleton
Golgi apparatus
Intellectual disability
Lysosome
Membrane
Phosphoprotein
Postsynaptic cell membrane
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q12955	Ankyrin-G
Q8NAK2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	IMP
plasma membrane organization	IMP
cytoskeleton organization	IEA
signal transduction	IEA
axonogenesis	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction

vesicle-mediated transport [inference]

Golgi vesicle transport

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

mitotic cell cycle process [inference]

mitotic cytokinesis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

cellular component assembly [inference]

membrane assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

membrane organization [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

magnesium ion homeostasis

inorganic ion homeostasis [inference]

magnesium ion homeostasis

response to stimulus [inference]

response to chemical [inference]

response to metal ion [inference]

response to magnesium ion [inference]

cellular response to magnesium ion

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

protein localization to axon

protein localization to cell periphery [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport [inference]

Golgi vesicle transport

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein location in membrane [inference]

maintenance of protein location in plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

regulation of potassium ion transport

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of cellular localization [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of protein targeting to membrane

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of cellular process [inference]

regulation of membrane depolarization [inference]

regulation of membrane depolarization during action potential [inference]

regulation of membrane depolarization during cardiac muscle cell action potential [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

signal transduction

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling

regulation of cell communication by electrical coupling [inference]

positive regulation of cell communication by electrical coupling

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

regulation of homotypic cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of cell communication by electrical coupling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion

positive regulation of protein targeting to membrane

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of cellular localization [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

regulation of membrane depolarization [inference]

regulation of membrane depolarization during action potential [inference]

regulation of membrane depolarization during cardiac muscle cell action potential [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane depolarization [inference]

positive regulation of membrane depolarization during cardiac muscle cell action potential

positive regulation of membrane potential

regulation of molecular function [inference]

regulation of transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

regulation of delayed rectifier potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of potassium ion transmembrane transporter activity [inference]

negative regulation of voltage-gated potassium channel activity [inference]

negative regulation of delayed rectifier potassium channel activity

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
lysosome	ISS
lysosome	IEA
endoplasmic reticulum	TAS
Golgi apparatus	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane

sarcolemma

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse [inference]

neuromuscular junction

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

tight junction [inference]

bicellular tight junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

sarcoplasmic reticulum

Golgi apparatus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spectrin-associated cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

sarcoplasmic reticulum

Golgi apparatus

intracellular membraneless organelle [inference]

spectrin-associated cytoskeleton

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
structural constituent of cytoskeleton	IMP
structural constituent of cytoskeleton	IEA
protein binding	IPI
cytoskeletal protein binding	ISS
cytoskeletal anchor activity	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton

binding [inference]

protein binding

cytoskeletal protein binding

spectrin binding

transmembrane transporter binding

cell adhesion molecule binding [inference]

cadherin binding

protein-containing complex binding [inference]

spectrin binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

cytoskeletal anchor activity

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter activator activity [inference]

channel activator activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel activator activity

ion channel regulator activity [inference]

sodium channel regulator activity

transporter activator activity [inference]

channel activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ankyrin

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
Ankyrin, UPA domain
Death domain
Death-like domain superfamily
ZU5 domain

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0081202	autosomal recessive intellectual developmental disorder 37	Alliance of Genome Resources
DOID:3312	bipolar disorder	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources

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Last updated: April 6, 2026