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Guidelines
MIRAGE
glutamate ionotropic receptor NMDA type subunit 2D

Summary
Gene Symbol
  • GRIN2D
Organism
Homo sapiens (human)
NCBI Gene
2906
PubChem
2906
Alliance of Genome Resources
JoGo
GRIN2D
TogoVar
GRIN2D
Annotation
Keyword
  • 3D-structure
  • Calcium
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Epilepsy
  • Glycoprotein
  • Ligand-gated ion channel
  • Magnesium
  • Metal-binding
  • Methylation
  • Phosphoprotein
  • Postsynaptic cell membrane
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
Q59G17
O15399
  • EB11
  • Glutamate [NMDA] receptor subunit epsilon-4
  • N-methyl D-aspartate receptor subtype 2D
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 31 in total
GO Term Evidence Code PMID
startle response
monoatomic ion transport
ion transport
brain development
adult locomotory behavior
GO Hierarchy
Displaying entries 1 - 5 of 22 in total
GO Term Evidence Code PMID
endoplasmic reticulum membrane
plasma membrane
plasma membrane
plasma membrane
plasma membrane
GO Hierarchy
Displaying entries 1 - 5 of 20 in total
GO Term Evidence Code PMID
glutamate-gated receptor activity
glutamate-gated receptor activity
NMDA glutamate receptor activity
NMDA glutamate receptor activity
NMDA glutamate receptor activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Glutamate
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
NMDA glutamate receptor activity
excitatory postsynaptic potential
ligand-gated monoatomic ion channel activity
long-term synaptic potentiation
monoatomic ion channel activity
monoatomic ion transport
Displaying all 3 entries
InterPro
Ionotropic glutamate receptor
Periplasmic binding protein-like I
Receptor, ligand binding region
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0080456 developmental and epileptic encephalopathy 46
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026