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Guidelines

MIRAGE

electron transfer flavoprotein dehydrogenase

Summary

Gene Symbol

Etfdh

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

295143

KEGG Gene ID

PubChem

295143

Alliance of Genome Resources

RGD:735052

Annotation

Keyword

4Fe-4S
Acetylation
Electron transport
FAD
Mitochondrion inner membrane
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Transit peptide
Ubiquinone

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q66HF3
F2W8A8
F7ELJ5

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
response to oxidative stress	ISS
response to oxidative stress	ISO
biological_process	ND
electron transport chain	ISO
electron transport chain	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

electron transport chain

respiratory electron transport chain

catabolic process [inference]

lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IEA
mitochondrial inner membrane	ISO
mitochondrial inner membrane	IBA
mitochondrial inner membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
electron-transferring-flavoprotein dehydrogenase activity	ISO
electron-transferring-flavoprotein dehydrogenase activity	IBA
electron-transferring-flavoprotein dehydrogenase activity	IEA
electron transfer activity	ISO
electron transfer activity	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on the CH-NH group of donors [inference]

oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor [inference]

electron-transferring-flavoprotein dehydrogenase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

cation binding [inference]

metal ion binding

quinone binding

ubiquinone binding

metal cluster binding [inference]

iron-sulfur cluster binding

4 iron, 4 sulfur cluster binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

electron transfer activity

electron-transferring-flavoprotein dehydrogenase activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
mitochondrial membrane	PMID:16248429

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	66841	MGI:106100

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026