GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

pyruvate dehydrogenase E1 subunit alpha 1

Summary

Gene Symbol

Pdha1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29554

KEGG Gene ID

PubChem

29554

Alliance of Genome Resources

RGD:3286

Annotation

Keyword

Glucose metabolism
Magnesium
Metal-binding
Mitochondrion
Oxidoreductase
Phosphoprotein
Proteomics identification
Pyruvate
Reference proteome
Thiamine pyrophosphate
Transit peptide
Tricarboxylic acid cycle

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F7FKI5
Q4FZZ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **6 - 6** of 6 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
tricarboxylic acid cycle

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

sulfur compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

organophosphate biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

tricarboxylic acid cycle

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

pyruvate metabolic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

nucleoside phosphate biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

purine-containing compound biosynthetic process [inference]

acyl-CoA biosynthetic process [inference]

acetyl-CoA biosynthetic process [inference]

pyruvate decarboxylation to acetyl-CoA

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IBA
mitochondrion	IEA
mitochondrial matrix	IDA
mitochondrial matrix	IEA

GO Hierarchy

cellular component

protein-containing complex

catalytic complex [inference]

oxidoreductase complex [inference]

alpha-ketoacid dehydrogenase complex [inference]

pyruvate dehydrogenase complex

transferase complex [inference]

acetyltransferase complex [inference]

pyruvate dehydrogenase complex

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
pyruvate dehydrogenase (acetyl-transferring) activity	ISS
pyruvate dehydrogenase (acetyl-transferring) activity	ISO
pyruvate dehydrogenase (acetyl-transferring) activity	IDA
pyruvate dehydrogenase (acetyl-transferring) activity	IBA
pyruvate dehydrogenase (acetyl-transferring) activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

pyruvate dehydrogenase (acetyl-transferring) activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
pyruvate dehydrogenase complex	PMID:7487891

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3649	pyruvate decarboxylase deficiency	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	18597	MGI:97532
Homo sapiens	5160	HGNC:8806

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: [email protected]

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026