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Fc gamma receptor and transporter

Summary

Gene Symbol

Fcgrt

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29558

PubChem

29558

Alliance of Genome Resources

RGD:61811

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
Endosome
Glycoprotein
IgG-binding protein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JAW9	IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor
P13599	IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
immune response	IBA
humoral immune response	TAS	2911353
Fc-gamma receptor signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

humoral immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

response to stimulus [inference]

immune response

humoral immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

regulation of response to stimulus [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
plasma membrane	IEA
external side of plasma membrane	IBA
endosome membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	15598658
IgG receptor activity	TAS	2911353
IgG binding	ISO
IgG binding	IEA
beta-2-microglobulin binding	IDA	2911353

GO Hierarchy

molecular function

binding [inference]

antigen binding [inference]

peptide antigen binding

protein binding

beta-2-microglobulin binding

amide binding [inference]

peptide binding [inference]

peptide antigen binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

IgG binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

immunoglobulin receptor activity [inference]

IgG receptor activity

immune receptor activity [inference]

immunoglobulin receptor activity [inference]

IgG receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

t-cell surface glycoprotein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
antigen processing and presentation, endogenous lipid antigen via MHC class Ib
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
endogenous lipid antigen binding
exogenous lipid antigen binding
immune response
lipopeptide binding
positive regulation of T cell mediated cytotoxicity

Displaying **all 7** entries
InterPro
Immunoglobulin C1-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
MHC class I-like antigen recognition-like superfamily
MHC class I-like antigen recognition-like
MHC classes I/II-like antigen recognition protein

Ortholog

Displaying entries **31 - 40** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	29199	Xenbase:XB-GENE-484711
Xenopus tropicalis	29558	Xenbase:XB-GENE-484711
Xenopus tropicalis	243864	Xenbase:XB-GENE-484711
Xenopus tropicalis	365212	Xenbase:XB-GENE-484711
Pan troglodytes	456208		PANTR18929
Canis lupus familiaris	476414		CANLF00801
Macaca mulatta	718859		MACMU00223
Monodelphis domestica	100030352		MONDO22823
Ovis aries	100144766		SHEEP05673
Equus caballus	100147583		HORSE01175