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gamma-glutamyltransferase 5

Summary

Gene Symbol

Ggt5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29566

KEGG Gene ID

PubChem

29566

Alliance of Genome Resources

RGD:2684

Annotation

Keyword

Acyltransferase
Glutathione biosynthesis
Glycoprotein
Leukotriene biosynthesis
Protease
Reference proteome
Signal-anchor
Transmembrane helix
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QWE9	Gamma-glutamyl leukotrienase Gamma-glutamyl transpeptidase-related enzyme Gamma-glutamyltransferase 5 Gamma-glutamyltransferase-like activity 1 Gamma-glutamyltranspeptidase 5 Leukotriene-C4 hydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
proteolysis	ISO
amino acid metabolic process	ISO
fatty acid metabolic process	ISO
glutathione metabolic process	IEA
glutathione biosynthetic process

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

cellular process [inference]

metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

modified amino acid metabolic process [inference]

glutathione metabolic process

modified amino acid catabolic process [inference]

glutathione catabolic process

modified amino acid biosynthetic process [inference]

glutathione biosynthetic process

sulfur compound metabolic process [inference]

glutathione metabolic process

sulfur compound biosynthetic process [inference]

sulfur compound catabolic process [inference]

glutathione catabolic process

catabolic process [inference]

modified amino acid catabolic process [inference]

glutathione catabolic process

sulfur compound catabolic process [inference]

glutathione catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

modified amino acid biosynthetic process [inference]

glutathione biosynthetic process

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

sulfur compound biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

amino acid metabolic process

lipid metabolic process [inference]

fatty acid metabolic process

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

fatty acid derivative metabolic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

protein metabolic process [inference]

proteolysis

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

response to stimulus [inference]

response to stress

defense response [inference]

inflammatory response

response to oxidative stress

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
peptidyltransferase activity	ISS
peptidyltransferase activity	ISO
leukotriene-C(4) hydrolase activity	ISS
leukotriene-C(4) hydrolase activity	ISO
leukotriene-C(4) hydrolase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

peptidyltransferase activity

hydrolase activity [inference]

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione gamma-glutamate hydrolase

catalytic activity, acting on a protein [inference]

peptidyltransferase activity

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione gamma-glutamate hydrolase

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

peptidyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

gamma-glutamyltransferase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
glutathione catabolic process
glutathione hydrolase activity

Displaying **all 4** entries
InterPro
Gamma-glutamyltranspeptidase, large subunit, C-terminal domain
Gamma-glutamyltranspeptidase, small subunit
Gamma-glutamyltranspeptidase
Nucleophile aminohydrolases, N-terminal

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	23887	MGI:1346063
Caenorhabditis elegans	171619	WB:WBGene00016906
Homo sapiens	2687	HGNC:4260
Saccharomyces cerevisiae S288C	851006	SGD:S000004290

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements