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Guidelines

MIRAGE

transforming growth factor beta receptor 3

Summary

Gene Symbol

Tgfbr3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29610

KEGG Gene ID

PubChem

29610

Alliance of Genome Resources

RGD:61821

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
Extracellular matrix
Glycoprotein
Phosphoprotein
Proteoglycan
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P26342	Betaglycan Transforming growth factor beta receptor III
A6KPK0	Betaglycan Transforming growth factor beta receptor III
A0ABK0LF96

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 80 in total

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GO Term	Evidence Code	PMID
blood vessel development	ISO
vasculogenesis	ISO
osteoblast differentiation	ISO
response to hypoxia	IEP
in utero embryonic development	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction

metabolic process [inference]

collagen metabolic process

cell population proliferation [inference]

muscle cell proliferation [inference]

striated muscle cell proliferation [inference]

cardiac muscle cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis involved in coronary vascular morphogenesis

osteoblast differentiation

myeloid cell differentiation [inference]

erythrocyte differentiation [inference]

definitive erythrocyte differentiation

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cardiac epithelial to mesenchymal transition

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

cardiac cell development [inference]

cardiac fibroblast cell development [inference]

epicardium-derived cardiac fibroblast cell development

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly

transforming growth factor beta receptor complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

transforming growth factor beta receptor complex assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue remodeling [inference]

blood vessel remodeling

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

muscular septum morphogenesis

cardiac muscle tissue morphogenesis [inference]

ventricular cardiac muscle tissue morphogenesis

ventricular compact myocardium morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

trabecula morphogenesis [inference]

heart trabecula morphogenesis

anatomical structure formation involved in morphogenesis [inference]

trabecula formation [inference]

heart trabecula formation

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

regeneration [inference]

animal organ regeneration

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

cardiac cell development [inference]

cardiac fibroblast cell development [inference]

epicardium-derived cardiac fibroblast cell development

animal gross anatomical part developmental process [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

animal organ development

animal organ regeneration

gland development [inference]

liver development

roof of mouth development

secondary palate development

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis involved in coronary vascular morphogenesis

osteoblast differentiation

myeloid cell differentiation [inference]

erythrocyte differentiation [inference]

definitive erythrocyte differentiation

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cardiac epithelial to mesenchymal transition

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

cardiac cell development [inference]

cardiac fibroblast cell development [inference]

epicardium-derived cardiac fibroblast cell development

response to stimulus [inference]

response to stress [inference]

response to hypoxia

immune response

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to gonadotropin [inference]

response to peptide hormone [inference]

response to luteinizing hormone

response to chemical [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to gonadotropin [inference]

response to peptide hormone [inference]

response to luteinizing hormone

response to lipid [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to luteinizing hormone

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to luteinizing hormone

response to alcohol [inference]

response to prostaglandin E

response to ketone [inference]

response to prostaglandin E

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of growth [inference]

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of developmental growth [inference]

regulation of organ growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell migration

negative regulation of epithelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of growth [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cardiac muscle cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of cellular component organization [inference]

negative regulation of extracellular matrix organization [inference]

negative regulation of extracellular matrix assembly

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

negative regulation of multicellular organismal process [inference]

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

regulation of developmental growth [inference]

regulation of organ growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

positive regulation of developmental process [inference]

positive regulation of developmental growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

regulation of multicellular organismal development [inference]

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of SMAD protein signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cardiac muscle cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

regulation of cellular component biogenesis [inference]

regulation of extracellular matrix assembly [inference]

negative regulation of extracellular matrix assembly

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cardiac muscle cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic process involved in development [inference]

negative regulation of apoptotic process involved in morphogenesis

negative regulation of cell differentiation [inference]

negative regulation of epithelial to mesenchymal transition

negative regulation of cellular component organization [inference]

negative regulation of extracellular matrix organization [inference]

negative regulation of extracellular matrix assembly

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

regulation of cellular component organization [inference]

negative regulation of cellular component organization [inference]

negative regulation of extracellular matrix organization [inference]

negative regulation of extracellular matrix assembly

regulation of extracellular matrix organization [inference]

regulation of extracellular matrix assembly [inference]

negative regulation of extracellular matrix assembly

negative regulation of extracellular matrix organization [inference]

negative regulation of extracellular matrix assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell migration

negative regulation of epithelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration [inference]

positive regulation of cell migration involved in sprouting angiogenesis

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

negative regulation of epithelial cell migration

regulation of organ growth [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of organ growth [inference]

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

negative regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of heart growth [inference]

regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

regulation of cardiac muscle cell proliferation [inference]

positive regulation of cardiac muscle cell proliferation

positive regulation of heart growth [inference]

positive regulation of cardiac muscle tissue growth [inference]

positive regulation of cardiac muscle cell proliferation

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
extracellular region	IDA
extracellular region	IEA
obsolete extracellular space
cytoplasm	ISO
endoplasmic reticulum	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

inhibin-betaglycan-ActRII complex

cellular anatomical structure [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 34 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	ISO
transmembrane signaling receptor activity	IEA
transforming growth factor beta receptor activity	ISO
transforming growth factor beta receptor activity	TAS
transforming growth factor beta receptor activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding

type II transforming growth factor beta receptor binding

growth factor binding [inference]

protein domain specific binding [inference]

PDZ domain binding

cytokine binding [inference]

SMAD binding

protein-containing complex binding [inference]

activin binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding

heparin binding

sulfur compound binding [inference]

heparin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

coreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular space	PMID:2592419

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	21814	MGI:104637
Homo sapiens	7049	HGNC:11774

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Last updated: April 6, 2026