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paraoxonase 2

Summary

Gene Symbol

Pon2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

296851

KEGG Gene ID

PubChem

296851

Alliance of Genome Resources

RGD:1309954

Annotation

Keyword

Calcium
Disulfide bond
Glycoprotein
Hydrolase
Membrane
Metal-binding
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6AXM8	Aromatic esterase 2 Serum aryldialkylphosphatase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
response to oxidative stress	IEP
response to toxic substance	IBA
carboxylic acid catabolic process	IBA
lactone catabolic process	ISO
lactone catabolic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

lactone catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

carboxylic acid catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process

lactone metabolic process [inference]

lactone catabolic process

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

response to chemical [inference]

response to toxic substance

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IBA
extracellular region	IEA
plasma membrane	ISO
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane

plasma membrane

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
arylesterase activity	IBA
arylesterase activity	IEA
protein homodimerization activity	ISO
metal ion binding
acyl-L-homoserine-lactone lactonohydrolase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

arylesterase activity

lactonohydrolase activity [inference]

acyl-L-homoserine-lactone lactonohydrolase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

serum paraoxonase/arylesterase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
arylesterase activity
hydrolase activity
metal ion binding
response to toxic substance

Displaying **all 2** entries
InterPro
Arylesterase
Six-bladed beta-propeller, TolB-like

Rhea

RHEA:17309

a phenyl acetate + H₂O

H⁺ + acetate + a phenol

Enzyme

3.1.1.2

PMID

RHEA:22576

H₂O + an N-acyl-L-homoserine lactone

H⁺ + an N-acyl-L-homoserine

Enzyme

3.1.1.81

PMID

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	330260	MGI:106687
Caenorhabditis elegans	171999	WB:WBGene00017089
Caenorhabditis elegans	187297	WB:WBGene00010775
Homo sapiens	5445	HGNC:9205
Danio rerio	447803	ZFIN:ZDB-GENE-040912-6
Xenopus tropicalis	448598	Xenbase:XB-GENE-491654

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements