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hydroxysteroid 17-beta dehydrogenase 10

Summary

Gene Symbol

HSD17B10

Organism

Homo sapiens (human)

External Links

NCBI Gene

3028

KEGG Gene ID

[""]

PubChem

3028

Alliance of Genome Resources

HGNC:4800

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Disease variant
Fatty acid metabolism
Intellectual disability
Mitochondrion nucleoid
NAD
Neurodegeneration
Oxidoreductase
Proteomics identification
Reference proteome
Steroid metabolism
tRNA processing

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99714	17-beta-estradiol 17-dehydrogenase 2-methyl-3-hydroxybutyryl-CoA dehydrogenase 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)) 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 3-hydroxyacyl-CoA dehydrogenase type II 3alpha(or 20beta)-hydroxysteroid dehydrogenase 7-alpha-hydroxysteroid dehydrogenase Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Mitochondrial ribonuclease P protein 2 Short chain dehydrogenase/reductase family 5C member 1 Short-chain type dehydrogenase/reductase XH98G2 Type II HADH
A0A0S2Z410	17-beta-estradiol 17-dehydrogenase 2-methyl-3-hydroxybutyryl-CoA dehydrogenase 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)) 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 3-hydroxyacyl-CoA dehydrogenase type II 3alpha(or 20beta)-hydroxysteroid dehydrogenase 7-alpha-hydroxysteroid dehydrogenase Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Mitochondrial ribonuclease P protein 2 Short chain dehydrogenase/reductase family 5C member 1 Short-chain type dehydrogenase/reductase XH98G2 Type II HADH

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
tRNA 3'-terminal CCA addition	IDA
L-isoleucine catabolic process	IDA
L-isoleucine catabolic process	IEA
lipid metabolic process	TAS
fatty acid metabolic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial RNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

mitochondrial RNA 3'-end processing [inference]

mitochondrial tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

ketone metabolic process [inference]

brexanolone metabolic process

hormone metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial RNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

mitochondrial RNA 3'-end processing [inference]

mitochondrial tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

macromolecule modification [inference]

RNA modification [inference]

RNA methylation [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

mitochondrial RNA modification [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

macromolecule methylation [inference]

RNA methylation [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

mitochondrial RNA modification [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

RNA modification [inference]

RNA methylation [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

mitochondrial RNA modification [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

mitochondrial RNA modification [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

RNA modification [inference]

RNA methylation [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

mitochondrial RNA modification [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial RNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

mitochondrial RNA 3'-end processing [inference]

mitochondrial tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

RNA 5'-end processing [inference]

mitochondrial RNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

tRNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

tRNA processing [inference]

tRNA modification [inference]

tRNA methylation [inference]

mitochondrial tRNA methylation

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 3'-end processing

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification [inference]

mitochondrial tRNA methylation

tRNA 5'-end processing [inference]

mitochondrial tRNA 5'-end processing

RNA 3'-end processing [inference]

mitochondrial RNA 3'-end processing [inference]

mitochondrial tRNA 3'-end processing

tRNA 3'-end processing

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

branched-chain amino acid metabolic process [inference]

isoleucine metabolic process [inference]

L-isoleucine catabolic process

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid metabolic process [inference]

isoleucine metabolic process [inference]

L-isoleucine catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

lipid metabolic process

fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

steroid metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

branched-chain amino acid metabolic process [inference]

isoleucine metabolic process [inference]

L-isoleucine catabolic process

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid metabolic process [inference]

isoleucine metabolic process [inference]

L-isoleucine catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

L-isoleucine catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

proteinogenic amino acid catabolic process [inference]

L-isoleucine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-isoleucine catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

bile acid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
cytoplasm	TAS
mitochondrion	ISS
mitochondrion	EXP
mitochondrion	NAS
mitochondrion	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

mitochondrial protein-containing complex [inference]

mitochondrial ribonuclease P complex

intracellular protein-containing complex [inference]

endonuclease complex [inference]

endoribonuclease complex [inference]

ribonuclease P complex [inference]

mitochondrial ribonuclease P complex

catalytic complex [inference]

endonuclease complex [inference]

endoribonuclease complex [inference]

ribonuclease P complex [inference]

mitochondrial ribonuclease P complex

transferase complex [inference]

methyltransferase complex [inference]

tRNA methyltransferase complex

ribonucleoprotein complex [inference]

ribonuclease P complex [inference]

mitochondrial ribonuclease P complex

cellular anatomical structure [inference]

cytoplasm

nucleoid [inference]

mitochondrial nucleoid

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

membraneless organelle [inference]

intracellular membraneless organelle [inference]

mitochondrial nucleoid

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular membraneless organelle [inference]

mitochondrial nucleoid

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
tRNA binding	IDA
RNA binding	HDA
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity	EXP
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity	IDA
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity	IEA