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Fc gamma receptor 3A

Summary

Gene Symbol

Fcgr3a

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

304966

KEGG Gene ID

PubChem

304966

Alliance of Genome Resources

RGD:1303067

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
IgE-binding protein
IgG-binding protein
Immunity
Immunoglobulin domain
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8L2QKY4
Q6XPU4	CD16-2 FcgammaRIV

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
antibody-dependent cellular cytotoxicity	ISO
antibody-dependent cellular cytotoxicity	IBA
T cell mediated cytotoxicity
dendritic cell antigen processing and presentation	ISO
dendritic cell antigen processing and presentation	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

myeloid leukocyte mediated immunity [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

lymphocyte mediated immunity [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

T cell mediated immunity [inference]

T cell mediated cytotoxicity

B cell mediated immunity [inference]

immunoglobulin mediated immune response [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

leukocyte degranulation [inference]

natural killer cell degranulation

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

B cell mediated immunity [inference]

immunoglobulin mediated immune response [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

antigen processing and presentation [inference]

dendritic cell antigen processing and presentation

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

macrophage activation

lymphocyte activation [inference]

natural killer cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

macrophage activation

lymphocyte activation [inference]

natural killer cell activation

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

granzyme-mediated programmed cell death signaling pathway

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

transmembrane transport [inference]

protein transmembrane transport

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

macrophage activation

lymphocyte activation [inference]

natural killer cell activation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

acute inflammatory response [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

B cell mediated immunity [inference]

immunoglobulin mediated immune response [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus [inference]

hypersensitivity [inference]

type II hypersensitivity [inference]

type IIa hypersensitivity [inference]

antibody-dependent cellular cytotoxicity

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

establishment of localization [inference]

transport [inference]

protein transport [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

transmembrane transport [inference]

protein transmembrane transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

Fc receptor-mediated immune complex endocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

establishment of protein localization [inference]

protein transport [inference]

establishment of localization in cell [inference]

leukocyte degranulation [inference]

natural killer cell degranulation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of bone resorption

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of response to stimulus [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

granzyme-mediated programmed cell death signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of tissue remodeling [inference]

regulation of bone remodeling [inference]

regulation of bone resorption [inference]

positive regulation of bone resorption

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of natural killer cell proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of bone resorption

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of natural killer cell activation [inference]

positive regulation of natural killer cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of natural killer cell proliferation

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
obsolete extracellular space
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

Fc receptor complex [inference]

Fc-gamma receptor III complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
IgE receptor activity	ISO
IgE receptor activity	IEA
IgG receptor activity	ISO
IgG receptor activity	IBA
IgG receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein-containing complex binding [inference]

immunoglobulin binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

immunoglobulin receptor activity [inference]

IgE receptor activity

IgG receptor activity

low-affinity IgG receptor activity

immune receptor activity

immunoglobulin receptor activity [inference]

IgE receptor activity

IgG receptor activity

low-affinity IgG receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cell surface	PMID:19106808

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	246256	MGI:2179523
Homo sapiens	2214	HGNC:3619
Homo sapiens	2215	HGNC:3620

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements