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MIRAGE
huntingtin interacting protein 1

Summary
Gene Symbol
  • HIP1
Organism
Homo sapiens (human)
NCBI Gene
3092
KEGG Gene ID
PubChem
3092
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Actin-binding
  • Activator
  • Alternative splicing
  • Apoptosis
  • Chromosomal rearrangement
  • Coiled coil
  • Cytoplasm
  • Cytoplasmic vesicle
  • Differentiation
  • Endocytosis
  • Membrane
  • Neurodegeneration
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Transcription regulation
Proteins
Displaying all 2 entries
UniProt Protein Name
B4DK46
O00291
  • Huntingtin-interacting protein I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 26 in total
GO Term Evidence Code PMID
endocytosis
endocytosis
apoptotic process
actin filament organization
regulation of endocytosis
GO Hierarchy
Displaying entries 1 - 5 of 23 in total
GO Term Evidence Code PMID
acrosomal vesicle
nucleus
nucleus
cytoplasm
cytoplasm
GO Hierarchy
Displaying entries 1 - 5 of 27 in total
GO Term Evidence Code PMID
actin binding
epidermal growth factor receptor binding
structural constituent of cytoskeleton
protein binding
phospholipid binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
huntingtin interacting protein
Functional Category
  • E: Amino acid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying all 10 entries
Gene Ontology
actin binding
actin filament binding
actin filament organization
clathrin adaptor activity
clathrin binding
clathrin coat assembly
clathrin light chain binding
phosphatidylinositol-3,4-bisphosphate binding
phosphatidylinositol-3,5-bisphosphate binding
phospholipid binding
Displaying all 7 entries
InterPro
AP180 N-terminal homology (ANTH) domain
ENTH domain
ENTH/VHS
Huntingtin-interacting protein 1, clathrin-binding domain
I/LWEQ domain superfamily
I/LWEQ domain
Sla2 family
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026