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aminoadipate-semialdehyde synthase

Summary

Gene Symbol

Aass

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

30956

KEGG Gene ID

PubChem

30956

Alliance of Genome Resources

MGI:1353573

Annotation

Keyword

Acetylation
Mitochondrion
Multifunctional enzyme
NAD
NADP
Oxidoreductase
Reference proteome
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99K67	LKR/SDH
Q3UEQ9	LKR/SDH

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
generation of precursor metabolites and energy	TAS
obsolete lysine catabolic process
L-lysine catabolic process	ISO
L-lysine catabolic process	IDA
L-lysine catabolic process	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy

catabolic process [inference]

amino acid catabolic process [inference]

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid metabolic process [inference]

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid metabolic process [inference]

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-lysine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-lysine catabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
mitochondrion	ISS
mitochondrion	ISO
mitochondrion	TAS
mitochondrion	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
saccharopine dehydrogenase activity	IBA
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	ISO
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	IDA
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	IMP
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-NH group of donors [inference]

oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [inference]

saccharopine dehydrogenase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha-aminoadipic semialdehyde synthase mitochondrial

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 6** entries
Gene Ontology
L-lysine catabolic process to acetyl-CoA via saccharopine
catalytic activity
lysine biosynthetic process via aminoadipic acid
lysine metabolic process
oxidoreductase activity
saccharopine dehydrogenase activity

Displaying **all 5** entries
InterPro
Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
NAD(P)-binding domain superfamily
Saccharopine dehydrogenase, NADP binding domain
Saccharopine dehydrogenase-like, C-terminal