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alpha actinin

Summary

Gene Symbol

Actn

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene: 31166
PubChem: 31166

Annotation

Keyword

Actin-binding
Alternative splicing
Calcium
Coiled coil
Cytoplasm
Metal-binding
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 4** entries
UniProt	Protein Name
F0JAG6	F-actin cross-linking protein
M9PGA7	F-actin cross-linking protein
P18091	F-actin cross-linking protein
M9MS06	F-actin cross-linking protein

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
actin cytoskeleton organization	IMP
actin cytoskeleton organization	IBA
sarcomere organization	IDA
sarcomere organization	IMP
actin filament bundle assembly	IMP

GO Hierarchy

biological process

cellular process [inference]

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

cellular developmental process [inference]

cell development [inference]

muscle cell development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development

cellular developmental process [inference]

cell development [inference]

muscle cell development

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GO Term	Evidence Code	PMID
cytoplasm
plasma membrane	IBA
focal adhesion	TAS
Z disc	IDA
Z disc	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

Z disc

cell junction

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell projection

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton [inference]

cortical actin cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton [inference]

cortical actin cytoskeleton

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
actin binding	IPI
calcium ion binding	IEA
protein binding	IPI
protein-containing complex binding	IEA
actin filament binding	IMP

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding

actin filament binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha actinin

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
actin binding
actin cytoskeleton organization
actin filament binding
calcium ion binding

Displaying **all 8** entries
InterPro
Actinin-type actin-binding domain, conserved site
CH domain superfamily
Calponin homology domain
EF-hand domain pair
EF-hand domain
EF-hand, Ca insensitive
Spectrin repeat
Spectrin/alpha-actinin