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Guidelines

MIRAGE

MAM domain containing glycosylphosphatidylinositol anchor 2

Summary

Gene Symbol

Mdga2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

314180

PubChem

314180

Alliance of Genome Resources

RGD:735131

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Immunoglobulin domain
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8I6AD32
P60756	MAM domain-containing protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 12** of 12 in total

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GO Term	Evidence Code	PMID
regulation of synaptic membrane adhesion	ISO
regulation of presynapse assembly	ISO

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord motor neuron differentiation

cell motility [inference]

cell migration [inference]

neuron migration

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process

pattern specification process

behavior [inference]

motor behavior

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord motor neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of developmental process [inference]

regulation of synapse maturation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of synaptic membrane adhesion

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of synapse maturation

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of synaptic membrane adhesion

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
side of membrane	IEA
postsynaptic density membrane	IDA	35532105
postsynaptic density membrane	IMP	35532105
glutamatergic synapse	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

side of membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mam domain-containing

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
MAM domain

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	161357	Xenbase:XB-GENE-6046933	HUMAN19240
Xenopus tropicalis	314180	Xenbase:XB-GENE-6046933
Mus musculus	320772	Xenbase:XB-GENE-6046933	MOUSE08304
Pan troglodytes	467448		PANTR08675
Canis lupus familiaris	480310		CANLF17883
Macaca mulatta	703237		MACMU42561
Monodelphis domestica	100010868		MONDO07124
Equus caballus	100064457		HORSE16645
Ornithorhynchus anatinus	100084336		ORNAN06529
Callithrix jacchus	100399471		CALJA02114

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 4, 2025