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Guidelines

MIRAGE

phosphatidylinositol glycan anchor biosynthesis, class B

Summary

Gene Symbol

Pigb

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

315807

KEGG Gene ID

rno:315807

PubChem

315807

Alliance of Genome Resources

RGD:1307251

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
D3ZYY8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
GPI anchor biosynthetic process	ISO
GPI anchor biosynthetic process	IBA
GPI anchor biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor biosynthetic process

glycolipid biosynthetic process [inference]

GPI anchor biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
alpha-1,2-mannosyltransferase activity	IBA
glycosyltransferase activity	IEA
dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity	ISO
dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

alpha-1,2-mannosyltransferase activity

dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity

GPI mannosyltransferase activity [inference]

dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mannosyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
alpha-1,2-mannosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
GPI mannosyltransferase

KEGG BRITE Database

Orthology

K05286

Name

GPI mannosyltransferase 3 [EC:2.4.1.-]

References

8861954

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05922	2.4.1.-	G73277FY G74840NI	G92405XV

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013391
Gene Name: phosphatidylinositol glycan anchor biosynthesis, class B

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	55981	MGI:1891825
Caenorhabditis elegans	13184808	WB:WBGene00194986
Drosophila melanogaster	38446	FB:FBgn0035464
Homo sapiens	9488	HGNC:8959
Saccharomyces cerevisiae S288C	852735	SGD:S000003110
Danio rerio	393448	ZFIN:ZDB-GENE-040426-1216

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026