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Guidelines
MIRAGE
heterogeneous nuclear ribonucleoprotein U
Summary
- Gene Symbol
-
- HNRNPU
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ADP-ribosylation
- ATP-binding
- Acetylation
- Activator
- Alternative splicing
- Biological rhythms
- Centromere
- Chromatin regulator
- Chromosome
- Citrullination
- Cytoskeleton
- DNA-binding
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disease variant
- Epilepsy
- Host-virus interaction
- Isopeptide bond
- Kinetochore
- Methylation
- Mitosis
- Nucleus
- Phosphoprotein
- Proteomics identification
- RNA-binding
- Reference proteome
- Repressor
- Ribonucleoprotein
- Spliceosome
- Transcription regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| alternative mRNA splicing, via spliceosome |
|
|
| regulation of alternative mRNA splicing, via spliceosome |
|
|
| mRNA splicing, via spliceosome |
|
|
| osteoblast differentiation |
|
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol |
|
|
| cell surface |
|
|
| cell surface |
|
|
| membrane |
|
|
| nuclear matrix |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding |
|
|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding |
|
|
| RNA polymerase II complex binding |
|
|
| TFIIH-class transcription factor complex binding |
|
|
| DNA binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- heterogeneous nuclear ribonucleoprotein u
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080418 | developmental and epileptic encephalopathy 54 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 51810 | MGI:1858195 | |
| 178421 | WB:WBGene00012769 |
