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MIRAGE
heat shock transcription factor 1
Summary
- Gene Symbol
-
- HSF1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Centromere
- Chromosome
- Cytoskeleton
- DNA repair
- DNA-binding
- Direct protein sequencing
- Host-virus interaction
- Isopeptide bond
- Kinetochore
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Stress response
- Transcription regulation
- Ubl conjugation
- mRNA processing
- mRNA transport
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00613 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| MAPK cascade |
|
|
| embryonic placenta development |
|
|
| DNA repair |
|
|
| regulation of DNA-templated transcription |
|
GO Hierarchy
- response to activity
biological process
cellular process [inference]
response to stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinetochore |
|
|
| chromatin |
|
|
| euchromatin |
|
|
| heterochromatin |
|
|
| spindle pole |
|
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- heat shock factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| sequence-specific DNA binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12858 | Huntington's disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 15499 | MGI:96238 | |
| 852806 | SGD:S000003041 |
