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MIRAGE
5-hydroxytryptamine receptor 3A

Summary
Gene Symbol
  • HTR3A
Organism
Homo sapiens (human)
NCBI Gene
3359
PubChem
3359
Alliance of Genome Resources
JoGo
HTR3A
TogoVar
HTR3A
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Ligand-gated ion channel
  • Postsynaptic cell membrane
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
B4E398
  • 5-hydroxytryptamine receptor 3
  • Serotonin receptor 3A
  • Serotonin-gated ion channel receptor
P46098
  • 5-hydroxytryptamine receptor 3
  • Serotonin receptor 3A
  • Serotonin-gated ion channel receptor
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 17 in total
GO Term Evidence Code PMID
monoatomic ion transport
ion transport
calcium ion transport
serotonin receptor signaling pathway
serotonin receptor signaling pathway
GO Hierarchy
Displaying entries 1 - 5 of 14 in total
GO Term Evidence Code PMID
transmembrane signaling receptor activity
ion channel activity
monoatomic ion channel activity
extracellular ligand-gated monoatomic ion channel activity
excitatory extracellular ligand-gated monoatomic ion channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
acetylcholine receptor subunit alpha
Functional Category
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
  • X: Mobilome: prophages, transposons
Displaying all 4 entries
Gene Ontology
extracellular ligand-gated monoatomic ion channel activity
ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
Displaying all 9 entries
InterPro
5-hydroxytryptamine 3 receptor, A subunit
5-hydroxytryptamine 3 receptor
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:9778 irritable bowel syndrome
DOID:9975 cocaine dependence
DOID:9976 heroin dependence
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026