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alkaline ceramidase 2

Summary

Gene Symbol

ACER2

Aliases

ALKCDase2
FLJ41587

Organism

Homo sapiens (human)

External Links

NCBI Gene

340485

HGNC

23675

KEGG Gene ID

hsa:340485

PubChem

340485

Alliance of Genome Resources

HGNC:23675

JoGo

ACER2

TogoVar

ACER2

Annotation

Keyword

Alternative splicing
Calcium
Glycoprotein
Golgi apparatus
Hydrolase
Metal-binding
Proteomics identification
Reference proteome
Sphingolipid metabolism
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KVV5
Q5QJU3	Acylsphingosine deacylase 3-like N-acylsphingosine amidohydrolase 3-like

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
negative regulation of cell-matrix adhesion	IDA
sphingolipid metabolic process	IEA
ceramide metabolic process	IEA
cellular response to DNA damage stimulus	IDA
DNA damage response	IDA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

metabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

sphingolipid catabolic process

ceramide catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process

ceramide catabolic process

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingolipid catabolic process

ceramide catabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

lipid catabolic process [inference]

sphingolipid catabolic process

ceramide catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

response to chemical [inference]

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to lipid [inference]

response to retinoic acid

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

response to oxygen-containing compound [inference]

response to retinoic acid

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell adhesion mediated by integrin

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process

regulation of catabolic process [inference]

regulation of autophagy

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of glycoprotein biosynthetic process

regulation of protein metabolic process [inference]

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell adhesion mediated by integrin

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cell adhesion mediated by integrin [inference]

negative regulation of cell adhesion mediated by integrin

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell adhesion mediated by integrin

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
Golgi apparatus	IDA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
N-acylsphingosine amidohydrolase activity	TAS
N-acylsphingosine amidohydrolase activity	IDA
N-acylsphingosine amidohydrolase activity	IMP
N-acylsphingosine amidohydrolase activity	IBA