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Serpin 28Dc

Summary

Gene Symbol

Spn28Dc

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

34091

KEGG Gene ID

PubChem

34091

Alliance of Genome Resources

FB:FBgn0031973

Annotation

Keyword

Developmental protein
Glycoprotein
Immunity
Melanin biosynthesis
Reference proteome
Secreted
Serine protease inhibitor
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VLU4	Serpin-28D

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
immune system process
response to wounding	IMP
negative regulation of melanization defense response	IMP
melanin biosynthetic process
negative regulation of proteolysis	ISM

GO Hierarchy

biological process

immune system process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

pigment biosynthetic process [inference]

melanin biosynthetic process

response to stimulus [inference]

response to stress [inference]

response to wounding

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of innate immune response [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

negative regulation of innate immune response [inference]

negative regulation of melanization defense response

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

regulation of secondary metabolic process [inference]

regulation of melanization defense response [inference]

negative regulation of melanization defense response

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis

negative regulation of melanization defense response

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	ISM
extracellular region	IMP
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

Displaying 1 entry
GO Term	Evidence Code	PMID
serine-type endopeptidase inhibitor activity	IEA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

serpin

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
serine-type endopeptidase inhibitor activity

Displaying **all 6** entries
InterPro
Serpin domain
Serpin family
Serpin superfamily, domain 1
Serpin superfamily, domain 2
Serpin superfamily
Serpin, conserved site

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
membrane	FB:FBrf0231198

Ortholog

Displaying entries **1 - 10** of 41 in total

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Species	Gene ID	Alliance of Genome Resources
Mus musculus	12401	MGI:88278
Mus musculus	18816	MGI:107173
Mus musculus	12258	MGI:894696
Mus musculus	16625	MGI:102848
Mus musculus	20700	MGI:891971
Mus musculus	20701	MGI:891970
Mus musculus	20702	MGI:891969
Mus musculus	20703	MGI:891968
Mus musculus	20704	MGI:891967
Mus musculus	20714	MGI:98377