GlyCosmos Portal

Submissions

Fas cell surface death receptor

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

355

KEGG Gene ID

PubChem

355

Alliance of Genome Resources

HGNC:11920

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Calmodulin-binding
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Palmitate
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A8Q3SIR6	Apo-1 antigen Apoptosis-mediating surface antigen FAS FASLG receptor
P25445	Apo-1 antigen Apoptosis-mediating surface antigen FAS FASLG receptor
K9J972	Apo-1 antigen Apoptosis-mediating surface antigen FAS FASLG receptor
Q59FU8	Apo-1 antigen Apoptosis-mediating surface antigen FAS FASLG receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

1

2

3

4

5

6

Next ›

Last »
GO Term	Evidence Code	PMID
apoptotic process	TAS
apoptotic process	IDA
apoptotic process	IEA
activation-induced cell death of T cells	IBA
immune response	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

Fas signaling pathway

extrinsic apoptotic signaling pathway

extrinsic apoptotic signaling pathway via death domain receptors

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

extrinsic apoptotic signaling pathway via death domain receptors

necroptotic signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process

neuron apoptotic process [inference]

motor neuron apoptotic process

leukocyte apoptotic process [inference]

lymphocyte apoptotic process [inference]

T cell apoptotic process [inference]

activation-induced cell death of T cells

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

cellular response to chemical stress [inference]

cellular response to hyperoxia

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to hyperoxia

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels [inference]

cellular response to hyperoxia

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

cellular response to chemical stress [inference]

cellular response to hyperoxia

response to starvation [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

response to amino acid starvation [inference]

cellular response to amino acid starvation

response to hyperoxia [inference]

cellular response to hyperoxia

immune response

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to oxygen levels [inference]

response to increased oxygen levels [inference]

cellular response to increased oxygen levels [inference]

cellular response to hyperoxia

response to hyperoxia [inference]

cellular response to hyperoxia

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels [inference]

cellular response to hyperoxia

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

response to amino acid starvation [inference]

cellular response to amino acid starvation

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to hyperoxia

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels [inference]

cellular response to hyperoxia

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to amino acid starvation

cellular response to chemical stress [inference]

cellular response to hyperoxia

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to hyperoxia

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels [inference]

cellular response to hyperoxia

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

Fas signaling pathway

extrinsic apoptotic signaling pathway

extrinsic apoptotic signaling pathway via death domain receptors

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

extrinsic apoptotic signaling pathway via death domain receptors

necroptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of programmed cell death [inference]

regulation of apoptotic process

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway

negative regulation of apoptotic process

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

Displaying entries **1 - 5** of 21 in total

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	IEA
cytosol	NAS
plasma membrane	EXP
plasma membrane	TAS
plasma membrane	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

death-inducing signaling complex

CD95 death-inducing signaling complex

cellular anatomical structure [inference]

membrane

plasma membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body

intracellular organelle [inference]

intracellular membraneless organelle [inference]

nuclear body

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

Displaying entries **6 - 9** of 9 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
kinase binding	IPI
signaling receptor activity	NAS
signaling receptor activity	TAS
identical protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

calmodulin binding

enzyme binding [inference]

kinase binding

identical protein binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

death receptor activity [inference]

tumor necrosis factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 20 in total

1

2

Next ›

Last »
DO ID	Disease Name	Source
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:0080797	nasal type extranodal NK/T-cell lymphoma	Alliance of Genome Resources
DOID:13133	HELLP syndrome	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources
DOID:2378	relapsing-remitting multiple sclerosis	Alliance of Genome Resources
DOID:7148	rheumatoid arthritis	Alliance of Genome Resources
DOID:0060704	lymphoproliferative syndrome	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14102	MGI:95484
Rattus norvegicus	246097	RGD:619831

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements