aquaporin 2

Summary
Gene Symbol
  • AQP2
Organism
Homo sapiens (human)
NCBI Gene
359
KEGG Gene ID
PubChem
359
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Cytoplasmic vesicle
  • Diabetes insipidus
  • Disease variant
  • Glycoprotein
  • Golgi apparatus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Transmembrane helix
  • Transport
Proteins
Displaying 1 entry
UniProt Protein Name
P41181
  • ADH water channel
  • Aquaporin-CD
  • Collecting duct water channel protein
  • WCH-CD
  • Water channel protein for renal collecting duct
Gene Ontology (GO)
Displaying entries 1 - 5 of 14 in total
GO Term Evidence Code PMID
renal water homeostasis
renal water homeostasis
renal water transport
water transport
water transport
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Aquaporin
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
water channel activity
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0081061 nephrogenic diabetes insipidus type 2
DOID:12387 nephrogenic diabetes insipidus
Ortholog
Displaying all 2 entries
Species Gene ID Alliance of Genome Resources
11827 MGI:1096865
25386 RGD:2142

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026