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aquaporin 4
Summary
- Gene Symbol
-
- AQP4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Disease variant
- Endosome
- Glycoprotein
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A5F9ZHR4 |
|
| P55087 |
|
| V9PBN7 |
|
| F1DSG4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| renal water homeostasis |
|
|
| water transport |
|
|
| water transport |
|
|
| intracellular water homeostasis |
|
|
| intracellular water homeostasis |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| cytoplasm |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding |
|
|
| water channel activity |
|
|
| water channel activity |
|
|
| water channel activity |
|
|
| water channel activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Aquaporin
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| water channel activity |
| InterPro |
|---|
| Aquaporin transporter |
| Aquaporin-like |
| Major intrinsic protein, conserved site |
| Major intrinsic protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080315 | megalencephalic leukoencephalopathy with subcortical cysts | |
| DOID:0080743 | transverse myelitis | |
| DOID:1210 | optic neuritis | |
| DOID:1432 | blindness | |
| DOID:3328 | temporal lobe epilepsy | |
| DOID:8869 | neuromyelitis optica | |
| DOID:9849 | Meniere's disease |
