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Dystroglycan

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

36773

KEGG Gene ID

PubChem

36773

Alliance of Genome Resources

FB:FBgn0034072

Annotation

Keyword

Cell membrane
Cytoskeleton
Disulfide bond
Glycoprotein
Nucleus
Phosphoprotein
Postsynaptic cell membrane
Proteomics identification
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q8STB9	Dystroglycan Dystrophin-associated glycoprotein 1
A1ZA89	Dystroglycan Dystrophin-associated glycoprotein 1
Q8WR08	Dystroglycan Dystrophin-associated glycoprotein 1
A0A0C4DHF6	Dystroglycan Dystrophin-associated glycoprotein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
morphogenesis of an epithelium	IBA
regulation of glycolytic process	IGI
cell adhesion	IEA
establishment or maintenance of cell polarity	IMP
germarium-derived egg chamber formation	IMP

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

establishment or maintenance of cell polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity

establishment or maintenance of epithelial cell apical/basal polarity

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

actomyosin structure organization [inference]

sarcomere organization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

reproductive process [inference]

developmental process involved in reproduction [inference]

oocyte axis specification

oocyte anterior/posterior axis specification

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

imaginal disc-derived wing vein specification

axis specification [inference]

oocyte axis specification

oocyte anterior/posterior axis specification

anterior/posterior axis specification [inference]

oocyte anterior/posterior axis specification

muscle attachment

developmental process [inference]

developmental process involved in reproduction [inference]

oocyte axis specification

oocyte anterior/posterior axis specification

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

brain morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium

anatomical structure formation involved in morphogenesis [inference]

germarium-derived egg chamber formation

anatomical structure development [inference]

nerve development

growth [inference]

developmental growth [inference]

growth of a germarium-derived egg chamber

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic activity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic activity

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycolytic process

regulation of phosphorus metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
nucleoplasm	IEA
cytoskeleton	IEA
plasma membrane	NAS
plasma membrane	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

glycoprotein complex [inference]

dystrophin-associated glycoprotein complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

cellular anatomical structure [inference]

membrane

plasma membrane

sarcolemma

plasma membrane region [inference]

basal plasma membrane

synaptic membrane [inference]

postsynaptic membrane

Z disc

cell junction [inference]

synapse [inference]

neuromuscular junction

T-tubule

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

Displaying **all 5** entries
GO Term	Evidence Code	PMID
laminin receptor activity	IDA
calcium ion binding	IEA
protein binding	IPI
structural constituent of muscle	NAS
laminin binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of muscle

binding [inference]

protein binding

laminin binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

laminin receptor activity

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 9** entries
Location	References
Z disc	PMID:21256839
sarcolemma	PMID:21256839
axon	PMID:17215867 PMID:18820475
basal plasma membrane	PMID:17355978 PMID:19250553
plasma membrane	PMID:19317464 PMID:24231130
dystroglycan complex	PMID:11502221
T-tubule	PMID:17881734
neuromuscular junction	PMID:18446215
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0112374	muscular dystrophy-dystroglycanopathy	Alliance of Genome Resources
DOID:9884	muscular dystrophy	Alliance of Genome Resources
DOID:0050453	lissencephaly	Alliance of Genome Resources