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integrin subunit alpha X

Summary

Gene Symbol

ITGAX

Organism

Homo sapiens (human)

External Links

NCBI Gene

3687

KEGG Gene ID

PubChem

3687

Alliance of Genome Resources

HGNC:6152

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Integrin
Magnesium
Metal-binding
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
H3BN02
P20702	CD11 antigen-like family member C Leu M5 Leukocyte adhesion glycoprotein p150,95 alpha chain Leukocyte adhesion receptor p150,95

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 23 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA
integrin-mediated signaling pathway	NAS
integrin-mediated signaling pathway	IBA
positive regulation of cell population proliferation	IMP
animal organ morphogenesis	TAS

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin [inference]

cell-cell adhesion mediated by integrin

cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to virus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of myelination

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of endothelial tube morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of endothelial tube morphogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of morphogenesis of an epithelium [inference]

regulation of endothelial tube morphogenesis [inference]

positive regulation of endothelial tube morphogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of endothelial tube morphogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of endothelial tube morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of myelination [inference]

positive regulation of myelination

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of myelination

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of myelination

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of endothelial tube morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of myelination [inference]

positive regulation of myelination

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IEA
integrin complex	TAS
integrin complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaX-beta2 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alphaX-beta2 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaX-beta2 complex

cellular anatomical structure [inference]

cell surface

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
integrin binding	TAS
protein binding	IPI
receptor tyrosine kinase binding	IPI
signaling receptor activity	TAS
signaling receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

cell adhesion molecule binding [inference]

integrin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	16411	MGI:96609

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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