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MIA SH3 domain ER export factor 3

Summary

Gene Symbol

MIA3

Organism

Homo sapiens (human)

External Links

NCBI Gene

375056

PubChem

375056

Alliance of Genome Resources

HGNC:24008

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Deafness
Diabetes mellitus
Dwarfism
ER-Golgi transport
Endoplasmic reticulum
Exocytosis
Glycoprotein
Intellectual disability
Methylation
Phosphoprotein
Protein transport
Reference proteome
SH3 domain
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5JRA6	C219-reactive peptide D320 Melanoma inhibitory activity protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
cell migration involved in sprouting angiogenesis	IMP	28341552
positive regulation of leukocyte migration	IDA	17726152
exocytosis	IMP	19269366
endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	27138255
endoplasmic reticulum to Golgi vesicle-mediated transport	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration [inference]

blood vessel endothelial cell migration [inference]

cell migration involved in sprouting angiogenesis

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

protein localization to endoplasmic reticulum exit site

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization

export from cell [inference]

secretion by cell [inference]

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

protein localization to endoplasmic reticulum exit site

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle cargo loading

COPII-coated vesicle cargo loading

secretion [inference]

secretion by cell [inference]

intracellular transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

export from cell [inference]

secretion by cell [inference]

establishment of protein localization [inference]

protein transport

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

protein localization to endoplasmic reticulum exit site

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of leukocyte migration

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of leukocyte migration

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of leukocyte migration

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

regulation of lymphocyte migration [inference]

negative regulation of lymphocyte migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of lymphocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	TAS
endoplasmic reticulum membrane	TAS
endoplasmic reticulum membrane	IDA	19269366
endoplasmic reticulum membrane	IBA
membrane	IDA	19269366

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum exit site

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	17726152 19269366 21525241 25202031 25416956 27138255 27170179 27551091 28442536 32296183
cargo receptor activity	IMP	27138255

GO Hierarchy

molecular function

binding [inference]

protein binding

cargo receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transport and Golgi organization protein 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
vesicle cargo loading

Ortholog

Displaying entries **11 - 20** of 50 in total

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Species	Gene ID	Orthologous MAtrix
Oryctolagus cuniculus	100351527	RABIT05721
Callithrix jacchus	100388104	CALJA17679
Callithrix jacchus	100410418	CALJA17679
Pongo abelii	100450028	PONAB17076
Nomascus leucogenys	100580164	NOMLE30424
Loxodonta africana	100653933	LOXAF13863
Cavia porcellus	100713212	CAVPO07572
Canis lupus familiaris	100855882	CANLF14368
Otolemur garnettii	100942700	OTOGA11005
Pan paniscus	100984883	PANPA03828

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements