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sister of tout-velu

Summary

Gene Symbol

sotv

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

3772101

KEGG Gene ID

dme:Dmel_CG8433

PubChem

3772101

Alliance of Genome Resources

FB:FBgn0029175

Annotation

Keyword

Developmental protein
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y169	Protein sister of tout-velu

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
glycoprotein biosynthetic process	IEA
heparan sulfate proteoglycan biosynthetic process	ISS
heparan sulfate proteoglycan biosynthetic process	IDA
heparan sulfate proteoglycan biosynthetic process	IMP
heparan sulfate proteoglycan biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
Golgi membrane	EXP
Golgi membrane	IEA
endoplasmic reticulum	IDA
endoplasmic reticulum membrane	IEA
Golgi apparatus	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

EXT1-EXT2 complex

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
acetylglucosaminyltransferase activity	IBA
glucuronosyltransferase activity	IEA
glycosyltransferase activity	IEA
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

glucuronosyltransferase activity

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

glucuronosyltransferase activity

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

exostosin

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
heparan sulfate proteoglycan biosynthetic process
transferase activity

Displaying **all 4** entries
InterPro
Exostosin, GT47 domain
Exostosin-like
Glycosyl transferase 64 domain
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K02367

Name

glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]

References

9756849

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05935	2.4.1.225	G13581JW	G74553IH
R10138	2.4.1.225	G18844FT	G70244WB

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
endoplasmic reticulum	PMID:14998928
Golgi apparatus	PMID:14998928
EXT1-EXT2 complex	PMID:14998928

Rhea

RHEA:16213

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.224

PMID

RHEA:20908

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.225

PMID

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14043	MGI:108050
Rattus norvegicus	311215	RGD:1307707
Homo sapiens	2132	HGNC:3513
Danio rerio	493780	ZFIN:ZDB-GENE-041124-3
Xenopus tropicalis	100151709	Xenbase:XB-GENE-867542

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements