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Standards Ontologies Notations
Guidelines
MIRAGE
coagulation factor XII

Summary
Gene Symbol
  • F12
Organism
Sus scrofa (pig)
NCBI Gene
397474
PubChem
397474
Annotation
Keyword
  • Disulfide bond
  • EGF-like domain
  • Fibrinolysis
  • Glycoprotein
  • Kringle
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
O97507
  • Hageman factor
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
blood coagulation
zymogen activation
fibrinolysis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
hepatocyte growth factor activator
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
blood coagulation
hydrolase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
zymogen activation
Displaying all 6 entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site
Ortholog
Displaying entries 1 - 10 of 45 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
2161 HUMAN82513
58992 MOUSE11430
280789 BOVIN33175
306761 RATNO12124
462304 PANTR36943
699875 MACMU38608
100031953 MONDO03992
100068589 HORSE08570
100313488 FELCA01148
100351481 RABIT09631
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025