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protein phosphatase 1 catalytic subunit alpha

Summary

Gene Symbol

PPP1CA

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 403609
PubChem: 403609

Annotation

Keyword

Cell division
Glycogen metabolism
Protein phosphatase
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8I3NRM8
A0A8C0PCF1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycogen metabolic process
protein dephosphorylation
circadian regulation of gene expression
regulation of circadian rhythm
entrainment of circadian clock by photoperiod

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cell division

rhythmic process [inference]

circadian rhythm [inference]

circadian regulation of gene expression

response to stimulus [inference]

response to external stimulus [inference]

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

photoperiodism [inference]

entrainment of circadian clock by photoperiod

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

regulation of circadian rhythm

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

circadian regulation of gene expression

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
nucleoplasm
nucleolus
cytoplasm	IEA	30032202
PTW/PP1 phosphatase complex

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex [inference]

PTW/PP1 phosphatase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein serine/threonine phosphatase activity	IEA	30032202
iron ion binding
phosphatase activity
myosin phosphatase activity
transition metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

myosin phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

myosin phosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
hydrolase activity

Displaying **all 4** entries
InterPro
Calcineurin-like phosphoesterase domain, ApaH type
Metallo-dependent phosphatase-like
Serine/Threonine protein phosphatase PP2A-like
Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	Orthologous MAtrix
Equus caballus	100059233	HORSE05617
Ciona intestinalis	100178587	CIOIN14330
Ailuropoda melanoleuca	100464499	AILME10661
Loxodonta africana	100673814	LOXAF04808
Sarcophilus harrisii	100915116	SARHA13357
Mustela putorius furo	101694049	MUSPF10497
Latimeria chalumnae	102362859	LATCH13357
Myotis lucifugus	102429857	MYOLU14234
Callorhinchus milii	103184322	CALMI29576
Ursus maritimus	103679611	URSMA26732