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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

glucuronidase beta

Summary

Gene Symbol

GUSB

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 403831
KEGG Gene ID: cfa:403831
PubChem: 403831

Annotation

Keyword

Disease variant
Glycoprotein
Glycosidase
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O18835

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA	22301074
glucuronoside catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process [inference]

glucuronoside catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process [inference]

glucuronoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process [inference]

glucuronoside catabolic process

glucuronoside metabolic process [inference]

glucuronoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process [inference]

glucuronoside catabolic process

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process [inference]

glucuronoside catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
lysosome

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
beta-glucuronidase activity	IEA	30032202
signaling receptor binding	IEA	30032202
carbohydrate binding	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

beta-glucuronidase activity

binding [inference]

protein binding [inference]

signaling receptor binding

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta glucuronidase

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
beta-glucuronidase activity
glucuronoside catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
signaling receptor binding

Displaying **all 10** entries
InterPro
Beta-Galactosidase/glucuronidase domain superfamily
Galactose-binding-like domain superfamily
Glycoside hydrolase family 2, catalytic domain
Glycoside hydrolase superfamily
Glycoside hydrolase, family 2, active site
Glycoside hydrolase, family 2, conserved site
Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich
Glycoside hydrolase, family 2
Glycosyl hydrolases family 2, sugar binding domain
Immunoglobulin-like fold

KEGG BRITE Database

Orthology

K01195

Name

beta-glucuronidase [EC:3.2.1.31]

References

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07818	3.2.1.31	G61095MM	G04652PB
R10830	3.2.1.31	G93263XO	G18375DW

Rhea

H₂O + a β-D-glucuronoside

an alcohol + D-glucuronate

Enzyme

3.2.1.31

PMID

Ortholog

Displaying entries **41 - 50** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cynoglossus semilaevis	103394912		CYNSE14760
Poecilia reticulata	103476056		POERE08126
Nannospalax galili	103738948		NANGA22632
Esox lucius	105008283		ESOLU19803
Pteropus vampyrus	105311411		PTEVA03623
Propithecus coquereli	105807071		PROCO12768
Microcebus murinus	105871011		MICMU05965
Salmo salar	106567395		SALSA30527
Equus asinus asinus	106831857		EQUAS20621
Cyprinodon variegatus	107090328		CYPVA14097

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025