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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

heat shock protein 90 beta family member 1

Summary

Gene Symbol

HSP90B1

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene

404019

KEGG Gene ID

PubChem

404019

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Calcium
Chaperone
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Hydrolase
Hydroxylation
Phosphoprotein
Reference proteome
Sarcoplasmic reticulum
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P41148	94 kDa glucose-regulated protein Heat shock protein 90 kDa beta member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein folding	IEA
ERAD pathway	ISS
ERAD pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

protein folding

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA
sarcoplasmic reticulum lumen	EXP
sarcoplasmic reticulum lumen	IEA
melanosome	ISS
melanosome	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen [inference]

sarcoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
ATP binding	IBA
ATP binding	IEA
ATP hydrolysis activity	EXP
ATP hydrolysis activity	IEA
unfolded protein binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

unfolded protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein folding chaperone [inference]

ATP-dependent protein folding chaperone

ATP-dependent activity [inference]

ATP-dependent protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Heat shock protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
ATP-dependent protein folding chaperone
cellular response to heat
disordered domain specific binding
nucleotide binding
protein stabilization
unfolded protein binding

Displaying **all 7** entries
InterPro
HSP90, C-terminal domain
Heat shock protein Hsp90 family
Heat shock protein Hsp90, N-terminal
Heat shock protein Hsp90, conserved site
Histidine kinase/HSP90-like ATPase superfamily
Histidine kinase/HSP90-like ATPase
Ribosomal protein uS5 domain 2-type superfamily

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026