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popeye domain cAMP effector 1

Summary

Gene Symbol

popdc1

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

415107

KEGG Gene ID

PubChem

415107

Alliance of Genome Resources

ZFIN:ZDB-GENE-040624-11

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell membrane
Developmental protein
Glycoprotein
Reference proteome
Tight junction
Transmembrane helix
cAMP-binding

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G9HVJ5
Q5PQZ7	Blood vessel epicardial substance

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
positive regulation of receptor recycling	ISS
heart looping	IMP
response to ischemia	ISS
outflow tract morphogenesis	IMP
cell adhesion

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell-cell adhesion [inference]

epithelial cell-cell adhesion

vesicle-mediated transport

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly [inference]

skeletal myofibril assembly

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly [inference]

skeletal myofibril assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly [inference]

skeletal myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly [inference]

skeletal myofibril assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly [inference]

skeletal myofibril assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

supramolecular fiber organization [inference]

myofibril assembly [inference]

skeletal myofibril assembly

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

heart process [inference]

heart contraction

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

embryonic morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of an epithelial sheet [inference]

epiboly

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

anatomical structure formation involved in morphogenesis [inference]

retina layer formation

cellular component assembly involved in morphogenesis [inference]

myofibril assembly [inference]

skeletal myofibril assembly

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

animal gross anatomical part developmental process [inference]

tissue development [inference]

epidermis development [inference]

skin epidermis development [inference]

establishment of skin barrier

epithelium development

skin epidermis development [inference]

establishment of skin barrier

muscle tissue development [inference]

striated muscle tissue development [inference]

skeletal muscle tissue development

animal organ development [inference]

heart development

retina development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation

cell development [inference]

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development

response to stimulus [inference]

response to stress [inference]

response to ischemia

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of signaling [inference]

positive regulation of receptor recycling

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of locomotion

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

regulation of action potential [inference]

regulation of cardiac muscle cell action potential

regulation of biological quality [inference]

regulation of cell shape

regulation of membrane potential

regulation of action potential [inference]

regulation of cardiac muscle cell action potential

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of hydrolase activity [inference]

regulation of GTPase activity

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
membrane	ISS
membrane	EXP
membrane	IEA
lateral plasma membrane	ISS
lateral plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

sarcolemma

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
structural molecule activity	ISS
cAMP binding	IBA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

cAMP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cytoplasm	PMID:23019331
membrane	PMID:23019331
cell junction	PMID:23019331
plasma membrane	PMID:23019331 PMID:26642364

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:6419	tetralogy of Fallot	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	11149	HGNC:1152
Xenopus tropicalis	100144641	Xenbase:XB-GENE-484277
Mus musculus	23828	MGI:1346013
Rattus norvegicus	365603	RGD:1561100

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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