GlyCosmos Portal

Annotation

Keyword

ANK repeat
Glycosyltransferase
Metal-binding
NAD
Nucleotidyltransferase
Reference proteome
Repeat
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9VBP3	Poly [ADP-ribose] polymerase Protein poly-ADP-ribosyltransferase tankyrase
A0A0B4KI19

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
segment polarity determination	IMP
larval chitin-based cuticle development	IMP
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IDA
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP
positive regulation of protein catabolic process	IMP

GO Hierarchy

biological process

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

periodic partitioning [inference]

segment polarity determination

molting cycle [inference]

molting cycle, chitin-based cuticle [inference]

cuticle development involved in chitin-based cuticle molting cycle [inference]

larval chitin-based cuticle development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of DNA metabolic process [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of telomere capping [inference]

positive regulation of telomere capping

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of telomere capping [inference]

positive regulation of telomere capping

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of chromosome organization [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

regulation of telomere capping [inference]

positive regulation of telomere capping

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance [inference]

positive regulation of telomere capping

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IDA
nucleus	IBA
cytoplasm	IBA
cytosol	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
NAD+ poly-ADP-ribosyltransferase activity	IDA
NAD+ poly-ADP-ribosyltransferase activity	IMP
NAD+ poly-ADP-ribosyltransferase activity	IGI
NAD+ poly-ADP-ribosyltransferase activity	IBA
NAD+ poly-ADP-ribosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

NAD+ poly-ADP-ribosyltransferase activity

NAD+-protein mono-ADP-ribosyltransferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

catalytic activity, acting on a protein [inference]

NAD+-protein mono-ADP-ribosyltransferase activity [inference]

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tankyrase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
NAD+ ADP-ribosyltransferase activity
transferase activity

Displaying **all 5** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
Poly(ADP-ribose) polymerase, catalytic domain
Sterile alpha motif domain
Sterile alpha motif/pointed domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
nucleus	PMID:27068743
cytosol	PMID:27068743

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	21951	MGI:1341087
Mus musculus	74493	MGI:1921743
Homo sapiens	80351	HGNC:15677
Homo sapiens	8658	HGNC:11941

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements