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MIRAGE
matrix metallopeptidase 16

Summary
Gene Symbol
  • MMP16
Organism
Homo sapiens (human)
NCBI Gene
4325
KEGG Gene ID
[""]
PubChem
4325
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cell membrane
  • Cleavage on pair of basic residues
  • Collagen degradation
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
P51512
  • MMP-X2
  • Membrane-type matrix metalloproteinase 3
  • Membrane-type-3 matrix metalloproteinase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 12 in total
GO Term Evidence Code PMID
skeletal system development
endochondral ossification
proteolysis
proteolysis
proteolysis
GO Hierarchy
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
metalloendopeptidase activity
metalloendopeptidase activity
metalloendopeptidase activity
metalloendopeptidase activity
enzyme activator activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
matrix metalloproteinase
Functional Category
  • E: Amino acid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
collagen catabolic process
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding
Displaying all 10 entries
InterPro
Hemopexin-like domain superfamily
Hemopexin-like domain
Hemopexin-like repeats
Metallopeptidase, catalytic domain superfamily
PGBD-like superfamily
Peptidase M10, metallopeptidase
Peptidase M10A, catalytic domain
Peptidase M10A
Peptidase, metallopeptidase
Peptidoglycan binding-like
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026