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Guidelines

MIRAGE

apolipophorin

Summary

Gene Symbol

apolpp

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

43827

PubChem

43827

Alliance of Genome Resources

FB:FBgn0087002

Annotation

Keyword

Cell projection
Cleavage on pair of basic residues
Direct protein sequencing
Glycoprotein
Heme
Lipid transport
Lipid-binding
Lipoprotein
Proteomics identification
Reference proteome
Secreted
Signal
Wnt signaling pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9V496	Retinoid- and fatty acid-binding glycoprotein
L0MPS3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
lipid transport	IDA
lipid transport	IMP
lipid transport	IEA
lipid transport involved in lipid storage	IMP
Wnt signaling pathway

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

lipoprotein transport

lipoprotein localization [inference]

lipoprotein transport

establishment of localization [inference]

transport [inference]

lipid transport

lipid transport involved in lipid storage

protein transport [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of canonical Wnt signaling pathway

positive regulation of smoothened signaling pathway

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	NAS
extracellular region	IDA
extracellular region	IEA
obsolete extracellular space
rhabdomere	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

cell projection [inference]

plasma membrane bounded cell projection [inference]

rhabdomere

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle

basal part of cell

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IPI
lipid carrier activity	IDA
lipid carrier activity	IMP
lipid carrier activity	IBA
lipid carrier activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

lipid binding [inference]

fatty acid binding

isoprenoid binding [inference]

retinoid binding [inference]

retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinol binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

cation binding [inference]

metal ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

alcohol binding [inference]

retinol binding

tetrapyrrole binding [inference]

heme binding

molecular carrier activity [inference]

lipid carrier activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

apolipophorins

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cellular response to estrogen stimulus
lipid transport
lipid transporter activity
response to estradiol

Displaying **all 7** entries
InterPro
Lipid transport protein, beta-sheet shell
Lipovitellin-phosvitin complex, superhelical domain
Vitellinogen, beta-sheet N-terminal
Vitellinogen, open beta-sheet, subdomain 1
Vitellinogen, open beta-sheet
Vitellogenin, N-terminal
von Willebrand factor, type D domain

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
endocytic vesicle	PMID:18198278
basal part of cell	PMID:22844248
membrane	FB:FBrf0231198
extracellular space	PMID:22844248 PMID:25275323

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1682	congenital heart disease	Alliance of Genome Resources

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026