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spinster

Summary

Gene Symbol

spin

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

45380

KEGG Gene ID

[""]

PubChem

45380

Alliance of Genome Resources

FB:FBgn0086676

Annotation

Keyword

Alternative splicing
Developmental protein
Endosome
Glycoprotein
Lipid transport
Lysosome
Oogenesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9GQQ0	Protein benchwarmer Protein diphthong

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
lipid transport
endocytosis	IMP
lysosome organization	IMP
courtship behavior	NAS
endosome to lysosome transport	IMP

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death

apoptotic process [inference]

apoptotic process involved in development [inference]

nurse cell apoptotic process

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

intercellular transport [inference]

endosome to lysosome transport

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

cell motility [inference]

cell migration [inference]

glial cell migration

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

synapse organization [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

neuromuscular junction development [inference]

synaptic assembly at neuromuscular junction

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation [inference]

oogenesis

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

mating behavior [inference]

courtship behavior

female mating behavior [inference]

regulation of female receptivity

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

nurse cell apoptotic process

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

larval central nervous system remodeling

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

oogenesis

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

nurse cell apoptotic process

cell differentiation [inference]

glial cell differentiation

cell development [inference]

germ cell development [inference]

oogenesis

growth [inference]

developmental growth [inference]

synaptic assembly at neuromuscular junction

locomotion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport

intercellular transport [inference]

endosome to lysosome transport

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosome to lysosome transport

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

transmembrane transport

import into cell [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of programmed cell death

regulation of apoptotic process [inference]

regulation of apoptotic process involved in development [inference]

regulation of nurse cell apoptotic process

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of reproductive process [inference]

regulation of nurse cell apoptotic process

regulation of biological quality [inference]

regulation of female receptivity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
lysosomal membrane	IEA
membrane	ISM
membrane	IBA
late endosome membrane	IDA
late endosome membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

presynapse

Displaying **all 3** entries
GO Term	Evidence Code	PMID
transmembrane transporter activity	ISM
transmembrane transporter activity	IBA
transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

spinster

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily
Protein spinster-like

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
late endosome membrane	PMID:12408844
membrane	FB:FBrf0231198
vesicle	PMID:21562262

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:14503	neuronal ceroid lipofuscinosis	Alliance of Genome Resources
DOID:1927	sphingolipidosis	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

GlyComb

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UniCarb-DR

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements