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MYD88 innate immune signal transduction adaptor

Summary

Gene Symbol

MYD88

Organism

Homo sapiens (human)

External Links

NCBI Gene

4615

PubChem

4615

Alliance of Genome Resources

HGNC:7562

JoGo

MYD88

TogoVar

MYD88

Annotation

Keyword

3D-structure
Alternative splicing
Antiviral defense
Cytoplasm
Disease variant
Inflammatory response
Innate immunity
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A3F2YP85
A0A494C0J8
A0A3B3ITY3
Q99836
A0A0A0MSI9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 89 in total

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GO Term	Evidence Code	PMID
toll-like receptor signaling pathway	NAS
response to molecule of fungal origin
leukocyte activation involved in inflammatory response
neutrophil activation involved in immune response
MyD88-dependent toll-like receptor signaling pathway	NAS

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium

myeloid leukocyte mediated immunity [inference]

neutrophil mediated immunity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium

lymphocyte mediated immunity [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

innate immune response

induced systemic resistance

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

granulocyte activation [inference]

neutrophil activation [inference]

neutrophil activation involved in immune response

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

granulocyte activation [inference]

neutrophil activation [inference]

neutrophil activation involved in immune response

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium

killing of cells of another organism [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

Toll signaling pathway

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

canonical NF-kappaB signal transduction

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

mononuclear cell differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization

chromatin remodeling

cellular component assembly [inference]

protein-containing complex assembly [inference]

canonical inflammasome complex assembly [inference]

NLRP3 inflammasome complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

canonical inflammasome complex assembly [inference]

NLRP3 inflammasome complex assembly

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

granulocyte activation [inference]

neutrophil activation [inference]

neutrophil activation involved in immune response

leukocyte activation involved in immune response [inference]

myeloid cell activation involved in immune response [inference]

neutrophil activation involved in immune response

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

animal organ development [inference]

skin development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

mononuclear cell differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to protozoan

defense response to symbiont [inference]

innate immune response

induced systemic resistance

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism [inference]

neutrophil-mediated killing of symbiont cell [inference]

neutrophil-mediated killing of bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to bacterium

defense response to virus

defense response to other organism [inference]

defense response to protozoan

defense response to symbiont [inference]

innate immune response

induced systemic resistance

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

innate immune response

induced systemic resistance

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to peptidoglycan

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to molecule of fungal origin

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to protozoan

defense response to symbiont [inference]

innate immune response

induced systemic resistance

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to peptidoglycan

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to molecule of fungal origin

response to other organism [inference]

response to protozoan [inference]

defense response to protozoan

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to protozoan

defense response to symbiont [inference]

innate immune response

induced systemic resistance

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

response to chemical [inference]

response to acid chemical [inference]

response to amino acid

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to peptide [inference]

response to cytokine [inference]

response to interleukin-1

response to nitrogen compound [inference]

response to oxygen-containing compound [inference]

response to peptidoglycan

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to alcohol [inference]

response to ethanol

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of leukocyte migration [inference]

regulation of neutrophil migration

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of neutrophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

Toll signaling pathway

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

canonical NF-kappaB signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of JNK cascade [inference]

positive regulation of JNK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

regulation of chemokine production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

positive regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of phosphorus metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

regulation of chemokine production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

positive regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of JNK cascade

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of neutrophil migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

regulation of chemokine production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

positive regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

positive regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

regulation of biological quality [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

RNA stabilization [inference]

mRNA stabilization [inference]

3'-UTR-mediated mRNA stabilization

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
nucleus	EXP
nucleus	IDA
nucleus	IEA
cytoplasm	EXP
cytoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

extrinsic component of membrane [inference]

extrinsic component of plasma membrane

extrinsic component of cytoplasmic side of plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IEA
Toll binding	IEA
death receptor binding	TAS
cytokine receptor binding	IEA
interleukin-1 receptor binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

catalytic activity, acting on a protein [inference]

ATP-dependent histone chaperone activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity

binding [inference]

protein binding

signaling receptor binding

Toll binding

cytokine receptor binding

interleukin-1 receptor binding

tumor necrosis factor receptor superfamily binding [inference]

death receptor binding

Toll-like receptor binding

growth factor receptor binding [inference]

interleukin-1 receptor binding

protein domain specific binding [inference]

TIR domain binding

identical protein binding

molecular adaptor activity

protein-macromolecule adaptor activity [inference]

signaling adaptor activity

molecular carrier activity [inference]

protein carrier activity [inference]

histone chaperone activity [inference]

ATP-dependent histone chaperone activity

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myeloid differentiation primary response protein MyD88

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
MyD88-dependent toll-like receptor signaling pathway
TIR domain binding
Toll signaling pathway
Toll-like receptor binding
defense response to Gram-positive bacterium
positive regulation of canonical NF-kappaB signal transduction
toll-like receptor 4 signaling pathway

Displaying **all 5** entries
InterPro
Death domain
Death-like domain superfamily
Myeloid differentiation primary response protein MyD88
Toll/interleukin-1 receptor homology (TIR) domain superfamily
Toll/interleukin-1 receptor homology (TIR) domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 11 in total

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DO ID	Disease Name	Source
DOID:0050745	diffuse large B-cell lymphoma	Alliance of Genome Resources
DOID:0060901	lymphoplasmacytic lymphoma	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:12253	testicular lymphoma	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:234	colon adenocarcinoma	Alliance of Genome Resources
DOID:3234	central nervous system lymphoma	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:612	primary immunodeficiency disease	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements