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Guidelines
MIRAGE
protein C, inactivator of coagulation factors Va and VIIIa

Summary
Gene Symbol
  • PROC
Organism
Canis lupus familiaris (dog)
NCBI Gene
476104
KEGG Gene ID
PubChem
476104
Annotation
Keyword
  • Blood coagulation
  • Calcium
  • Cleavage on pair of basic residues
  • Disulfide bond
  • EGF-like domain
  • Endoplasmic reticulum
  • Gamma-carboxyglutamic acid
  • Glycoprotein
  • Golgi apparatus
  • Hydroxylation
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
Q28278
  • Anticoagulant protein C
  • Autoprothrombin IIA
  • Blood coagulation factor XIV
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
blood coagulation
blood coagulation
negative regulation of apoptotic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
serine protease
Functional Category
  • E: Amino acid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
blood coagulation
hydrolase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
Displaying all 8 entries
InterPro
EGF-like domain
Gamma-carboxyglutamic acid-rich (GLA) domain
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026