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ATPase Na+/K+ transporting subunit beta 3

Summary

Gene Symbol

ATP1B3

Organism

Homo sapiens (human)

External Links

NCBI Gene

483

KEGG Gene ID

PubChem

483

Alliance of Genome Resources

HGNC:806

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Signal-anchor
Sodium/potassium transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P54709	Sodium/potassium-dependent ATPase subunit beta-3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
potassium ion transport	IEA
sodium ion transport	IEA
intracellular sodium ion homeostasis	IDA
intracellular sodium ion homeostasis	IBA
intracellular sodium ion homeostasis	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

regulation of potassium ion transport [inference]

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of membrane potential [inference]

membrane repolarization

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
plasma membrane	TAS
plasma membrane	IDA
sodium:potassium-exchanging ATPase complex	IDA
sodium:potassium-exchanging ATPase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
ATPase activator activity	IDA
ATPase activator activity	IBA
ATPase activator activity	IEA
protein binding	IPI
protein-macromolecule adaptor activity	IDA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

ATPase binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter regulator activity [inference]

transporter activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sodium/potassium-transporting ATPase subunit beta

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ATPase activator activity
intracellular sodium ion homeostasis

Displaying **all 2** entries
InterPro
Sodium/potassium-transporting ATPase subunit beta superfamily
Sodium/potassium-transporting ATPase subunit beta

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	11933	MGI:107788
Rattus norvegicus	25390	RGD:2172
Caenorhabditis elegans	182726	WB:WBGene00007646
Caenorhabditis elegans	181494	WB:WBGene00010117
Drosophila melanogaster	33953	FB:FBgn0015777
Drosophila melanogaster	33952	FB:FBgn0015776