NME/NM23 nucleoside diphosphate kinase 1

Summary
Gene Symbol
  • NME1
Organism
Homo sapiens (human)
NCBI Gene
4830
PubChem
4830
Alliance of Genome Resources
JoGo
NME1
TogoVar
NME1
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Cell membrane
  • Cytoplasm
  • Differentiation
  • Direct protein sequencing
  • Disulfide bond
  • Endocytosis
  • Glutathionylation
  • Hydrolase
  • Isopeptide bond
  • Kinase
  • Magnesium
  • Metal-binding
  • Neurogenesis
  • Nucleotide metabolism
  • Nucleus
  • Oxidation
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A384MTW7
P15531
  • Farnesyl diphosphate kinase NME1
  • Histidine protein kinase NME1
  • Metastasis inhibition factor nm23
  • NM23-H1
  • Non-specific serine/threonine protein kinase NME1
  • Nucleoside diphoshate kinase 1
  • Putative 3'-5'-DNA exonuclease NDK1
  • Putative granzyme A-activated DNA endonuclease
  • Tumor metastatic process-associated protein
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 33 in total
GO Term Evidence Code PMID
magnesium ion binding
DNA binding
RNA binding
DNA endonuclease activity
endodeoxyribonuclease activity
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Nucleoside diphosphate kinase
Functional Category
  • C: Energy production and conversion
  • F: Nucleotide transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 3 entries
DO ID Disease Name Source
DOID:2152 ovary epithelial cancer
DOID:3307 teratoma
DOID:769 neuroblastoma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026