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Guidelines

MIRAGE

natriuretic peptide receptor 2

Summary

Gene Symbol

NPR2

Organism

Homo sapiens (human)

External Links

NCBI Gene

4882

KEGG Gene ID

PubChem

4882

Alliance of Genome Resources

HGNC:7944

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Dwarfism
GTP-binding
Glycoprotein
Lyase
Osteogenesis
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix
cGMP biosynthesis

Proteins

Displaying 1 entry
UniProt	Protein Name
P20594	Atrial natriuretic peptide receptor type B Guanylate cyclase B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 71 in total

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GO Term	Evidence Code	PMID
MAPK cascade	IEA
ovarian follicle development	IEA
cumulus cell differentiation	IEA
blood vessel development	IEA
vasculogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

c-di-GMP signaling

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

receptor guanylyl cyclase signaling pathway

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

intracellular signal transduction

intracellular signaling cassette [inference]

MAPK cascade

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide metabolic process [inference]

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleotide biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cyclic nucleotide biosynthetic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

cyclic purine nucleotide metabolic process [inference]

cGMP metabolic process

cGMP biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cGMP metabolic process

cGMP biosynthetic process

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

purine ribonucleotide biosynthetic process [inference]

cGMP biosynthetic process

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cell population proliferation [inference]

chondrocyte proliferation

cell growth [inference]

developmental cell growth [inference]

collateral sprouting

cell cycle process [inference]

meiotic cell cycle process [inference]

meiotic cell cycle process involved in oocyte maturation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

oocyte development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

granulosa cell differentiation [inference]

cumulus cell differentiation

fat cell differentiation [inference]

white fat cell differentiation

cell development [inference]

germ cell development

oocyte development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to peptide

cellular response to nitrogen compound [inference]

cellular response to cGMP

cellular response to oxygen-containing compound [inference]

cellular response to cGMP

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis involved in innervation

execution phase of apoptosis

reproductive process [inference]

developmental process involved in reproduction [inference]

cumulus cell differentiation

germ cell development

oocyte development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

fertilization [inference]

single fertilization

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

oocyte development

meiotic cell cycle process [inference]

meiotic cell cycle process involved in oocyte maturation

multicellular organismal process [inference]

ossification [inference]

replacement ossification [inference]

endochondral ossification

system process [inference]

circulatory system process [inference]

blood circulation

digestive system process [inference]

gastric motility [inference]

gastric emptying

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

neuromuscular process [inference]

startle response

multicellular organism growth

organ growth [inference]

bone growth

tissue remodeling [inference]

blood vessel remodeling

developmental process [inference]

developmental process involved in reproduction [inference]

cumulus cell differentiation

germ cell development

oocyte development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

genitalia morphogenesis

appendage morphogenesis [inference]

limb morphogenesis

tube morphogenesis [inference]

digestive tract morphogenesis

post-anal tail morphogenesis

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis involved in innervation

developmental maturation [inference]

anatomical structure maturation [inference]

nerve maturation [inference]

cranial nerve maturation [inference]

vestibulocochlear nerve maturation

anatomical structure formation involved in morphogenesis [inference]

angiogenesis [inference]

angiogenesis involved in wound healing [inference]

vascular wound healing

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

smooth muscle tissue development

connective tissue development [inference]

growth plate cartilage development

nerve development

cranial nerve development [inference]

vestibulocochlear nerve development

tube development [inference]

digestive tract development

cell development [inference]

germ cell development

oocyte development

animal organ development [inference]

genitalia development [inference]

female genitalia development

cartilage development

cartilage development involved in endochondral bone morphogenesis [inference]

growth plate cartilage development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

appendage development [inference]

limb development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

granulosa cell differentiation [inference]

cumulus cell differentiation

fat cell differentiation [inference]

white fat cell differentiation

cell development [inference]

germ cell development

oocyte development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

collateral sprouting

developmental growth [inference]

multicellular organism growth

organ growth [inference]

bone growth

developmental cell growth [inference]

collateral sprouting

developmental growth involved in morphogenesis [inference]

collateral sprouting

response to stimulus [inference]

response to stress [inference]

response to wounding

response to external stimulus [inference]

startle response

response to endogenous stimulus [inference]

response to hormone

response to gonadotropin [inference]

response to luteinizing hormone

response to peptide hormone [inference]

response to luteinizing hormone

response to growth factor [inference]

response to fibroblast growth factor

response to chemical [inference]

response to hormone

response to gonadotropin [inference]

response to luteinizing hormone

response to peptide hormone [inference]

response to luteinizing hormone

response to organophosphorus [inference]

response to cGMP [inference]

cellular response to cGMP

cellular response to chemical stimulus [inference]

cellular response to peptide

cellular response to nitrogen compound [inference]

cellular response to cGMP

cellular response to oxygen-containing compound [inference]

cellular response to cGMP

response to peptide [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

response to granulocyte macrophage colony-stimulating factor [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

cellular response to peptide

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cGMP [inference]

cellular response to cGMP

response to peptide hormone [inference]

response to luteinizing hormone

cellular response to nitrogen compound [inference]

cellular response to cGMP

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to luteinizing hormone

response to cGMP [inference]

cellular response to cGMP

cellular response to oxygen-containing compound [inference]

cellular response to cGMP

response to salt

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to peptide

cellular response to nitrogen compound [inference]

cellular response to cGMP

cellular response to oxygen-containing compound [inference]

cellular response to cGMP

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

c-di-GMP signaling

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

negative regulation of cell cycle [inference]

negative regulation of meiotic cell cycle

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

negative regulation of reproductive process [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

regulation of cell maturation [inference]

regulation of oocyte maturation [inference]

negative regulation of oocyte maturation

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

receptor guanylyl cyclase signaling pathway

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

intracellular signal transduction

intracellular signaling cassette [inference]

MAPK cascade

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

regulation of cell maturation [inference]

regulation of oocyte maturation [inference]

negative regulation of oocyte maturation

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of cell maturation [inference]

negative regulation of oocyte maturation

negative regulation of cell cycle [inference]

negative regulation of meiotic cell cycle

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

negative regulation of cell cycle [inference]

negative regulation of meiotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

negative regulation of meiotic cell cycle

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

negative regulation of meiotic cell cycle

regulation of oocyte maturation [inference]

negative regulation of oocyte maturation

negative regulation of reproductive process [inference]

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of biological quality [inference]

regulation of blood pressure

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleus	IEA
cytoplasm	IEA
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
guanylate cyclase activity	IDA
guanylate cyclase activity	IMP
guanylate cyclase activity	IBA
guanylate cyclase activity	IEA
protein kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

cyclase activity [inference]

guanylate cyclase activity

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

lyase activity [inference]

phosphorus-oxygen lyase activity

guanylate cyclase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

hormone binding

peptide hormone binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

natriuretic peptide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10825	essential hypertension	Alliance of Genome Resources
DOID:0080050	acromesomelic dysplasia, Maroteaux type	Alliance of Genome Resources
DOID:0070316	Miura type epiphyseal chondrodysplasia	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	230103	MGI:97372
Rattus norvegicus	116564	RGD:620851
Caenorhabditis elegans	172051	WB:WBGene00020131

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026